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Table 3 Multivariate analysis of predictors of 90-day mortality

From: Impact of obesity on survival in COVID-19 ARDS patients receiving ECMO: results from an ambispective observational cohort

 

Odds ratio

95% CI

p value

Model A

 Age

1.135

1.004–1.285

0.044

 BMIa

0.775

0.644–0.934

0.007

 Charlson score

1.220

0.593–2.510

0.589

 High-flow nasal oxygen before intubation

0.963

0.075–12.357

0.977

 First wave

0.669

0.03–14.698

0.799

 RESP score

1.117

0.673–1.853

0.669

 Dexamethasone usea

5.211

0.375–72.412

0.219

 Hydroxychloroquine use

0.673

0.108–4.186

0.671

 Time from ICU admission to ECMO

1.108

0.951–1.291

0.187

Model B

 Age

1.187

1.035–1.362

0.014

 BMIa

0.631

0.462–0.862

0.004

 Charlson score

1.482

0.753–2.917

0.255

 High-flow nasal oxygen before intubation

1.674

0.132–21.228

0.691

 First wave

0.817

0.03–21.912

0.904

 PRESERVE score

0.508

0.242–1.067

0.074

 Dexamethasone useb

4.942

0.308–79.223

0.259

 Hydroxychloroquine use

0.499

0.074–3.361

0.475

 Time from ICU admission to ECMO

1.175

0.984–1.403

0.075

  1. Model A: variables included: (a) quantitative: age, BMI, RESP score, Charlson score, time from ICU (intensive care unit) admission to ECMO; (b) qualitative: pandemic waves (first vs. second), dexamethasone use, hydroxychloroquine use, high-flow nasal O2 before intubation. Hosmer–Lemeshow test p = 0.558
  2. Model B: variables included: (a) quantitative: age, BMI, PRESERVE score, Charlson score, time from ICU (intensive care unit) admission to ECMO; (b) qualitative: pandemic waves (first vs. second), dexamethasone use, hydroxychloroquine use, high-flow nasal O2 before intubation. Hosmer–Lemeshow test, p = 0.182
  3. BMI body mass index (g/m2), CI confidence interval, PRESERVE score [19] PRedicting dEath for SEvere ARDS on VV-ECMO score, RESP score [17] Respiratory Extracorporeal Membrane Oxygenation Survival Prediction Score
  4. a3 patients had missing data for BMI
  5. bPatients receiving dexamethasone 6 mg per day or equivalent dose of corticosteroids