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Table 1 Main general characteristics at ICU admission of overall patients and according to outcome at day 90 after in-ICU CA

From: Incidence, clinical characteristics, and outcome after unexpected cardiac arrest among critically ill adults with COVID-19: insight from the multicenter prospective ACICOVID-19 registry

Characteristic

All patients

(N = 146)

Favorable

(N = 30)

Unfavorable

(N = 116)

p value

Demographics

    

 Age, years

62 [55–70]

61 [54–69]

63 [56–69]

0.51

 Male gender

118 (81)

25 (83)

93 (80)

0.70

 Body mass index, kg/m2

29 [26–33]

30 [26–33]

29 [26–33]

0.66

Previous comorbidities

    

 Hypertension

80 (55)

12 (40)

78 (67)

0.07

 Diabetes

49 (34)

5 (17)

44 (38)

0.03

 Respiratory disease

17 (12)

4 (13)

13 (11)

0.75

 Malignancy

15 (10)

2 (7)

13 (11)

0.47

 Ischemic heart disease

13 (9)

2 (7)

11 (9)

0.63

 Moderate to severe chronic kidney diseasea

8 (5)

2 (7)

6 (5)

0.75

 Chronic heart failure

2 (1)

1 (3)

1 (1)

0.30

Charlson comorbidity index

3 [2–4]

2 [1–4]

3 [2–4]

0.20

Chronic previous treatments

    

 Angiotensin conversion enzyme/receptor blocker

51 (35)

7 (23)

44 (38)

0.14

 Calcium channel blocker

31 (21)

2 (7)

29 (25)

0.03

 Beta blocker

23 (16)

0 (0)

23 (20)

0.008

 Corticosteroid

8 (5)

0 (0)

8 (7)

0.14

Severity of illness at ICU admission

    

 SAPS-2

42 [32–57]

41 [32–44]

43 [30–61]

0.14

 SOFA

7 [4–11]

6 [4–10]

7 [4–12]

0.41

 Organ failures (SOFA organ sub-score ≥ 3)

    

  Respiratory

104 (71)

21 (70)

83 (72)

0.30

  Neurologic

47 (32)

10 (33)

37 (32)

0.82

  Circulatory

47 (32)

8 (27)

39 (34)

0.27

  Renal

22 (15)

3 (10)

19 (16)

0.28

  Hematologic

2 (2)

0 (0)

2 (2)

0.44

  Hepatic

1 (1)

0 (0)

1 (1)

0.59

 SOFA > 9

30 (21)

8 (27)

22 (19)

0.34

  1. Results are expressed as N (%) or median [25–75% interquartile range] unless expressed otherwise. Favorable outcome: modified Rankin scale ranging from 0 to 3 at day 90 after CA; unfavorable outcome: modified Rankin scale ranging from 4 to 6 at day 90 after CA; ICU: intensive care unit; CA: cardiac arrest; SAPS-2: simplified acute physiology score 2; SOFA: sepsis-related organ failure assessment score
  2. aModerate = creatinine > 3 mg/dl (270 μmol/l); severe = on dialysis