Characteristic | All patients (N = 146) | Favorable (N = 30) | Unfavorable (N = 116) | p value |
---|---|---|---|---|
Demographics | ||||
Age, years | 62 [55–70] | 61 [54–69] | 63 [56–69] | 0.51 |
Male gender | 118 (81) | 25 (83) | 93 (80) | 0.70 |
Body mass index, kg/m2 | 29 [26–33] | 30 [26–33] | 29 [26–33] | 0.66 |
Previous comorbidities | ||||
Hypertension | 80 (55) | 12 (40) | 78 (67) | 0.07 |
Diabetes | 49 (34) | 5 (17) | 44 (38) | 0.03 |
Respiratory disease | 17 (12) | 4 (13) | 13 (11) | 0.75 |
Malignancy | 15 (10) | 2 (7) | 13 (11) | 0.47 |
Ischemic heart disease | 13 (9) | 2 (7) | 11 (9) | 0.63 |
Moderate to severe chronic kidney diseasea | 8 (5) | 2 (7) | 6 (5) | 0.75 |
Chronic heart failure | 2 (1) | 1 (3) | 1 (1) | 0.30 |
Charlson comorbidity index | 3 [2–4] | 2 [1–4] | 3 [2–4] | 0.20 |
Chronic previous treatments | ||||
Angiotensin conversion enzyme/receptor blocker | 51 (35) | 7 (23) | 44 (38) | 0.14 |
Calcium channel blocker | 31 (21) | 2 (7) | 29 (25) | 0.03 |
Beta blocker | 23 (16) | 0 (0) | 23 (20) | 0.008 |
Corticosteroid | 8 (5) | 0 (0) | 8 (7) | 0.14 |
Severity of illness at ICU admission | ||||
SAPS-2 | 42 [32–57] | 41 [32–44] | 43 [30–61] | 0.14 |
SOFA | 7 [4–11] | 6 [4–10] | 7 [4–12] | 0.41 |
Organ failures (SOFA organ sub-score ≥ 3) | ||||
Respiratory | 104 (71) | 21 (70) | 83 (72) | 0.30 |
Neurologic | 47 (32) | 10 (33) | 37 (32) | 0.82 |
Circulatory | 47 (32) | 8 (27) | 39 (34) | 0.27 |
Renal | 22 (15) | 3 (10) | 19 (16) | 0.28 |
Hematologic | 2 (2) | 0 (0) | 2 (2) | 0.44 |
Hepatic | 1 (1) | 0 (0) | 1 (1) | 0.59 |
SOFA > 9 | 30 (21) | 8 (27) | 22 (19) | 0.34 |