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Table 3 Organ support and clinical outcomes in the cohort according to favorable or unfavorable outcome at day 90 after in-ICU CA

From: Incidence, clinical characteristics, and outcome after unexpected cardiac arrest among critically ill adults with COVID-19: insight from the multicenter prospective ACICOVID-19 registry

Variable

All patients

(N = 146)

Favorable

(N = 30)

Unfavorable

(N = 116)

p value

Organ support

    

 Duration of mechanical ventilation, days

15 [7–36]

33 [19–45]

14 [5–28]

 < 0.001

 Vasopressors

109 (82)

25 (83)

84 (72)

0.06

  Duration of vasopressor treatment, days

6 [3–11]

7 [4–16]

6 [2–11]

0.09

 Neuromuscular blocking agent

131 (90)

26 (87)

105 (91)

0.54

 Prone positioning

111 (76)

24 (80)

87 (75)

0.57

 Renal replacement therapy

66 (45)

12 (40)

54 (47)

0.52

  Duration of renal replacement therapy, days

5 [2–11]

6 [3–21]

5 [2–10]

0.29

 ECMO

20 (14)

4 (13)

16 (14)

0.95

Targeted temperature management

7 (5)

3 (10)

4 (3)

0.13

Outcome at ICU discharge

    

 Death

102 (70)

102 (88)

  New in-ICU CA occurrence

31 (21)

31 (27)

  Unsuccessful CPR attempt

29 (20)

29 (25)

  From WLST

21 (14)a

21 (18)

  From multi-organ failure

18 (12)

18 (16)

  From refractory ARDS

3 (2)

3 (3)

 Duration of ICU hospitalization, days

20 [8–42]

45 [28–71]

16 [7–33]

 < 0.001

Outcome at day 90 after in-ICU CA

    

 Died

106 (73)

106 (91)

-

 Remained hospitalized

2 (1)

0 (0)

2 (2)

0.47

 Duration of hospitalization, days

26 [10–54]

59 [46–94]

17 [8–38]

 < 0.001

Modified Rankin scale

    

 0

6 (4)

6 (20)

 1

9 (6)

9 (30)

 2

10 (7)

10 (33)

 3

5 (3)

5 (16)

 4

6 (4)

6 (7)

 5

4 (3)

4 (3)

  1. Results are expressed as N (%) or median [25–75% interquartile range] unless expressed otherwise. Favorable: modified Rankin scale ranging from 0 to 3 ay day 90 after CA; Unfavorable: modified Rankin scale ranging from 4 to 6 at day 90 after CA; ICU: intensive care unit; CA: cardiac arrest; ECMO: extracorporeal membrane of oxygenation; CPR: cardiopulmonary resuscitation; WLST: withdrawal of life-sustaining therapy; ARDS: acute respiratory distress syndrome
  2. aIncluding 4 WLST for neurological impairment and 17 WLST for other reasons