Overall | |
---|---|
No. of patients | 49 |
Age, mean (SD), years | 58.0 (14.1) |
Gender (male), n (%) | 27 (55%) |
Height, mean (SD), cm | 167.7 (10.5) |
Predicted body weight, mean (SD), kg | 61.9 (11.2) |
Ethnicity, n (%) | |
African American | 18 (37%) |
Caucasian | 17 (35%) |
Hispanic/Latino | 10 (20%) |
Asian | 4 (8%) |
Smoker, n (%) | 21 (43%) |
Smoking package years | 20 (3.5, 39) |
Cause of acute hypoxemic respiratory failure | |
COVID-19 pneumonia | 25 (51%) |
Postoperative respiratory failure | 10 (20%) |
Non-COVID-19 pneumonia | 5 (10%) |
Congestive heart failure | 5 (10%) |
Lung cancer | 3 (6%) |
Sickle cell anemia, acute chest | 1 (2%) |
Comorbidity, n (%) | |
Chronic lung disease | 8 (16%) |
Chronic heart disease | 17 (35%) |
Hypertension | 29 (59%) |
Diabetes mellitus | 13 (27%) |
Obesity (BMI ≥ 30 kg/m2) | 9 (18%) |
Obstructive sleep apnea | 7 (14%) |
Cancer | 15 (31%) |
HFNC parameters at study enrollment | |
FIO2, mean (SD) | 0.62 (0.16) |
SpO2, median (IQR), % | 94 (93, 95) |
SpO2/FIO2, mean (SD) | 160 (40) |
ROX index, mean (SD) | 7.65 (3.05) |
Gas flow, median (IQR), L/min | 45 (37.5, 50) |
Breathing measurement | |
Tidal volume, median (IQR), ml | 468 (399, 548) |
RR, median (IQR), bpm | 21 (18, 26) |
Ti, mean (SD), sec | 1.24 (0.41) |
Peak tidal inspiratory flow, mean (SD), L/min | 34 (9) |
Peak tidal inspiratory flow, median (IQR), L/min | 31 (27, 42) |