Table 2 Description and treatment of VAP caused by S. maltophilia
Variables | Total N = 130 | Alive at ICU discharge n = 65 | Dead at ICU discharge n = 65 | p-value |
|---|---|---|---|---|
Infection | ||||
Bacteremia | 4 (3.1) | 1 (1.5) | 3 (4.6) | 0.89 |
Polymicrobial | 58 (44.6) | 32 (49.2) | 26 (40) | 0.29 |
Duration of mechanical ventilation before onset of VAP, days | 12 [5–18] | 13.5 [5.5–19] | 10 [5–16] | 0.62 |
Treatment | ||||
No treatment | 38 (29.2) | 18 (13.8) | 20 (15.4) | 0.57 |
Monotherapy | 4 (0.03) | 3 (0.02) | 1 | |
Combination therapy (≥ 2) | 88 (67.7) | 44 (67.7) | 44 (67.7) | |
Trimethoprim/sulfamethoxazole | 80 (62.5) | 40 (62.5) | 40 (62.5) | 1 |
Fluoroquinolone | 84 (65.6) | 40 (62.5) | 44 (68.7) | 0.46 |
Ticarcillin–clavulanate | 39 (30.4) | 20 (31.3) | 19 (29.7) | 0.85 |
Ceftazidime | 9 (7.0) | 5 (7.8) | 4 (6.3) | 0.99 |
Duration of appropriate antibiotic therapy, days | 8 [5–14] | 9[6–14] | 7[3–12] | 0.12 |
Time to start of appropriate antibiotic therapy, days | 2 [1–3] | 2 [1, 2] | 2 [1–3] | 0.58 |