Table 2 Characteristics on ICU day-7 or day-14 of the development and test datasets of the SOSIC-7 and SOSIC-14 scores according to their 90-day survival status
From: Predicting 90-day survival of patients with COVID-19: Survival of Severely Ill COVID (SOSIC) scores
SOSIC-7 | SOSIC-14 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Development dataset (n = 2585) | Test dataset (n = 292) | Development dataset (n = 1164) | Test dataset (n = 185) | |||||||||
90-day status | 90-day status | 90-day status | 90-day status | |||||||||
Alive (1845) | Death (740) | P value | Alive (217) | Death (75) | P value | Alive (1251) | Death (413) | P value | Alive (142) | Death (43) | P value | |
On day-7 or day-14 in ICU | ||||||||||||
SOFA components | ||||||||||||
Respiratory | 3 (2–3) | 3 (3–4) | < 0.01 | 3 (2–3) | 3 (3–4) | < 0.01 | 3 (2–3) | 3 (3–4) | < 0.01 | 3 (2–3) | 3 (3–4) | 0.02 |
Cardiovascular | 3 (1–4) | 4 (3–4) | < 0.01 | 3 (1–4) | 4 (3–4) | < 0.01 | 3 (1–4) | 4 (3–4) | < 0.01 | 3 (1–4) | 4 (3–4) | 0.10 |
Renal | 2 (1–4) | 2 (1–4) | 0.20 | 2 (1–4) | 2 (2–4) | 0.5 | 2 (1–4) | 2 (1–4) | 0.3 | 2 (1–4) | 3 (2–4) | 0.20 |
Lactate, mmol/L | 1.3 (1.0–1.7) | 1.5 (1.2–1.9) | < 0.01 | 1.3 (1.0–1.7) | 1.4 (1.1–1.8) | 0.06 | 1.1 (0.8–1.5) | 1.3 (1.0–1.7) | < 0.01 | 1.2 (0.9–1.6) | 1.2 (0.9–1.5) | 0.60 |
Ventilation profilea | < 0.01 | 0.30 | < 0.01 | 0.02 | ||||||||
Standard oxygen therapy | 96 (5) | 4 (0.5) | 11 (5) | 1 (1) | 96 (8) | 0 (0) | 17 (12) | 0 (0) | ||||
High-flow oxygen | 98 (5) | 7 (1) | 15 (7) | 2 (3) | 40 (3) | 4 (1) | 6 (4) | 0 (0) | ||||
Noninvasive ventilation | 37 (2) | 10 (1) | 5 (2) | 1 (1) | 32 (3) | 3 (1) | 4 (3) | 1 (2) | ||||
Invasive MV | 1578 (87) | 714 (97) | 186 (86) | 71 (95) | 1040 (86) | 401 (98) | 110 (80) | 42 (98) | ||||
Since ICU admission | ||||||||||||
Invasive MV duration | 7 (6–7) | 7 (7–7) | < 0.01 | 7 (6–7) | 7 (6–7) | 0.40 | 14 (13–14) | 14 (13–14) | < 0.01 | 14 (13–14) | 14 (12–14) | 0.80 |
Extubation | 76 (5) | 8 (1) | < 0.01 | 8 (4) | 2 (3) | 0.90 | 153 (13) | 12 (3) | < 0.01 | 19 (14) | 4 (9) | 0.50 |
≥ 1 prone-positioning session | 1028 (63) | 531 (75) | < 0.01 | 127 (67) | 58 (82) | 0.02 | 923 (76) | 346 (86) | < 0.01 | 105 (77) | 35 (83) | 0.40 |
≥ 24 h continuous neuromuscular blockades | 1408 (86) | 653 (92) | < 0.01 | 151 (79) | 61 (86) | 0.20 | 1095 (91) | 384 (96) | < 0.01 | 122 (90) | 40 (95) | 0.40 |
≥ 1 VAP episode(s) | 597 (36) | 276 (41) | 0.02 | 57 (28) | 21 (30) | 0.70 | 738 (62) | 266 (69) | 0.01 | 82 (59) | 21 (50) | 0.30 |
Cardiac arrest | 26 (1) | 18 (2) | 0.06 | 2 (1) | 3 (4) | 0.11 | 44 (3) | 18 (4) | 0.40 | 2 (1) | 3 (7) | 0.08 |
Proven pulmonary embolism | 74 (4) | 39 (5) | 0.15 | 10 (5) | 4 (5) | 0.80 | 102 (8) | 42 (10) | 0.20 | 15 (11) | 6 (14) | 0.60 |