The effect of the volemic and cardiac status on brain oxygenation in patients with subarachnoid hemorrhage: a bi-center cohort study

Annals of Intensive Care

Table 1 Baseline characteristics, complications, and outcomes

Clinical characteristics		N = 60
Age in years		56 (47–65)
Female sex		37 (62)
Chronic heart failure		0 (0)
Previous myocardial infarction		3 (5)
Pre-existing hypertension		22 (37)
Smoking history		24 (40)
Admission H&H grade	1	3 (5)
	2	6 (10)
	3	14 (23)
	4	6 (10)
	5	31 (52)
GCS at ICU admission		3 (3–10)
LOC at ictus		36 (60)
Admission radiological characteristics
Modified Fisher Scale	1	2 (3)
	2	2 (3)
	3	13 (22)
	4	43 (72)
ICH present on admission CT scan		30 (50)
Hydrocephalus requiring EVD placement		42 (70)
Global cerebral edema		24 (40)
Aneurysm treatment
Endovascular coiling		31 (52)
Neurosurgical clipping		27 (45)
Non-aneurysmal SAH^a		2 (3)
Complications and treatment
Neurogenic myocardial stunning		23 (38)
Pneumonia		42 (70)
Ventriculitis		7 (12)
Vasospasm		48 (80)
Delayed cerebral ischemia		25 (42)
Noradrenaline, daily dose in mg^b		11 (5–25)
Dobutamine, daily dose in mg^b		33 (0–258)
Phenylephrine, daily dose in mg^b		0 (0–3)
Outcome characteristics
Length of ICU stay in days		28 (18–39)
In-hospital mortality		14 (23)
3-month mRS	0	2 (3)
	1	8 (13)
	2	6 (10)
	3	10 (17)
	4	9 (15)
	5	10 (17)
	6	15 (25)

Data are given in median (IQR) and counts (%)
SAH subarachnoid hemorrhage, H&H Hunt and Hess, LOC loss of consciousness, ICH intracerebral hemorrhage, EVD external ventricular drain, mRS modified Rankin Scale
^aAneurysm negative in repeated cerebral angiogram 2–3 weeks apart
^bWithin the first 10 days