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Table 3 Performance of the PIRO staging system for predicting hospital survival in each stage

From: Prospective international validation of the predisposition, infection, response and organ dysfunction (PIRO) clinical staging system among intensive care and general ward patients

 

Stage I (n = 431)

Stage II (n = 510)

Stage III (n = 601)

Stage IV (n = 96)

Sensitivity, 95% CI

30% (28–33)

62% (59–65)

95% (83–86)

5% (4–6)

Specificity, 95% CI

95% (91–97)

66% (60–72)

12% (9–17)

88% (83–91)

Negative likelihood ratio, 95% CI

0.7 (0.7–0.8)

0.6 (0.5–0.6)

0.4 (0.3–0.6)

1.1 (1.0–1.1)

Positive likelihood ratio, 95% CI

5.9 (3.5–9.9)

1.8 (1.5–2.2)

1.1 (1.0–1.1)

0.4 (0.3–0.6)

Negative predictive value, 95% CI

21% (20–21)

25% (23–27)

34% (25–43)

18% (16–20)

Positive predictive value, 95% CI

97% (95–98)

91% (89–92)

85% (84–86)

66% (57–75)

  1. CI confidence interval