Awake prone position reduces work of breathing in patients with COVID-19 ARDS supported by CPAP

Annals of Intensive Care

Table 1 Demographics and baseline characteristics of the study population

	Total population N = 40
Age, years	59 [53–68]
Male sex	26 (65)
Body mass index, kg/m²	27 [25–31]
Charlson comorbidity index	2 [1–3]
Arterial hypertension	16 (40)
Diabetes mellitus	5 (12)
Solid tumor	4 (10)
Immunosoppression	2 (5)
HACOR score at study start	3 [0–4]
SOFA score at study start	3 [2, 3]
SAPS II score at study start	24 [22–27]
Time from symptoms to hospital admission, days	6 [5–10]
Time from hospital admission to CPAP and proning, days	2 [2–4]
C-reactive protein, mg/L	60 [42–102]
D-dimers, μg/L	371 [248–575]
Lactate, mmol/L	1.3 [1.0–1.4]
ARDS classification
Mild	14 (35)
Moderate	22 (55)
Severe	4 (10)
PaO₂/ FiO₂ ratio, mmHg	166 [136–224]
PaO₂, mmHg	114 [90–141]
PaCO₂, mmHg	38 [35–42]
PEEP, cmH₂O	10 [8–10]
Dynamic lung compliance [ml/cmH₂O]	64 [42–89]
Requirement for endotracheal intubation	7 (18)
Mortality at 28 days	4 (10)

HACOR Heart Rate, Acidosis, Consciousness, Oxygenation, Respiratory Rate, SOFA Sequential Organ Failure Assessment, SAPS II Simplified Acute Physiology Score, CPAP continuous positive airway pressure, ARDS acute respiratory distress syndrome, PEEP positive end-expiratory pressure
Data are presented as counts (percentages) for dichotomous values or median [interquartile range] for continuous values unless otherwise specified