From: Awake prone position reduces work of breathing in patients with COVID-19 ARDS supported by CPAP
 | Supine N = 40 | Prone N = 40 | p | Mean difference†[95% CI] |
---|---|---|---|---|
Esophageal pressure swing, cmH2O | − 7 [− 9 to − 5] | − 6 [− 9 to − 5] | 0.306 | 0.4 [− 0.4 to 1.1] |
Dynamic transpulmonary pressure, cmH2O | 17 [14 to 19] | 16 [14 to 18] | 0.34 | − 0.4 [− 1.1 to 0.4] |
Modified pressure–time product, cmH2O/min | 152 [104 to 197] | 118 [90 to 150] |  < 0.001 | − 33 [− 47 to − 19] |
Work of breathing, cmH2O * L /min | 146 [120 to 185] | 114 [95 to 151] |  < 0.001 | − 27 [− 38 to − 17] |
Borg Dyspnea Scale 0—none 1—very light 2—light 3—moderate 4—rather intense | 29 (72) 3 (8) 5 (12) 1 (2) 2 (5) | 37 (92) 2 (5) 1 (2) 0 (0) 0 (0) | 0.005 | − 0.5 [− 0.8 to − 0.2] |
Non-invasive Work of Breathing Scale 1 2 3 4 | 20 (50) 12 (30) 5 (12) 3 (8) | 31 (78) 8 (20) 1 (2) 0 (0) | 0.001 | − 0.5 [− 0.9 to − 0.2] |