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Table 1 Changes in patients’ underlying characteristics between 2007 and 2018

From: Patterns of ICU admissions and outcomes in patients with solid malignancies over the revolution of cancer treatment

Characteristics

2007–2008

2009–2010

2011–2012

2013–2014

2015–2016

2017–2018

p

(n = 181)

(n = 230)

(n = 241)

(n = 263)

(n = 291)

(n = 319)

Proportions of concurrent ICU admissions (%)

6.1

7.5

7.4

7.2

8.4

10.2

 < 0.001

Age (years)

70 [59–78]

68 [59–76]

67 [60–75]

66 [57–75]

67 [59–74]

67 [60–74]

0.15

Male gender

126 (69.6)

143 (62.2)

152 (63.1)

159 (60.5)

163 (56)

201 (63)

0.87

Non-cancer comorbid conditions

       

 Hypertension

76 (42.0)

97 (42.2)

97 (40.2)

120 (45.6)

131 (45.0)

138 (43.3)

0.45

 Diabetes

38 (21.0)

44 (19.1)

31 (12.9)

60 (22.8)

55 (18.9)

61 (19.1)

0.88

 Cirrhosis

10 (5.5)

18 (7.8)

17 (7.1)

17 (6.5)

19 (6.5)

20 (6.3)

0.85

 Chronic renal failure

20 (11.0)

20 (8.7)

18 (7.5)

29 (11.0)

28 (9.6)

22 (6.9)

0.34

 Chronic heart failure

8 (4.4)

14 (6.1)

9 (3.7)

23 (8.7)

11 (3.8)

16 (5.0)

0.93

Type of cancer

      

 < 0.001

 Lung

50 (27.6)

55 (24.1)

50 (20.7)

60 (22.8)

69 (23.7)

95 (29.8)

 

 Gastrointestinal

25 (13.8)

44 (19.1)

72 (29.9)

90 (34.2)

86 (29.5)

80 (25.1)

 Urologic

51 (28.2)

63 (27.4)

48 (19.9)

47 (17.9)

47 (16.2)

58 (18.2)

 Breast

16 (8.8)

29 (12.7)

22 (9.1)

24 (9.1)

34 (11.7)

28 (8.8)

 Head and neck

12 (6.6)

11 (4.8)

12 (5.0)

5 (1.9)

7 (2.4)

7 (2.2)

 Gynaecologic

10 (5.5)

8 (3.5)

13 (5.4)

9 (3.4)

10 (3.4)

13 (4.1)

 Skin

1 (0.6)

3 (1.3)

2 (0.8)

3 (1.1)

10 (3.4)

7 (2.2)

 Others

16 (8.9)

17 (7.4)

22 (9.1)

25 (9.5)

28 (9.6)

31 (9.7)

Time from diagnosis to ICU admission (days)

259 [43–722]

237 [43–833]

254 [61–967]

291 [99–1024]

267 [57–914]

264 [70–736]

0.23

Stage a

      

0.004

 Localized

53 (29.3)

66 (28.7)

65 (27.0)

58 (22.1)

70 (24.1)

60 (18.8)

 Advanced

34 (18.8)

55 (23.9)

50 (20.7)

46 (17.5)

62 (21.3)

67 (21.0)

 Metastatic

88 (48.6)

106 (46.1)

125 (51.9)

157 (59.7)

156 (53.6)

192 (60.2)

Current cancer status

      

 < 0.001

 Newly diagnosed

62 (34.3)

72 (31.3)

71 (29.5)

58 (22.1)

96 (33.0)

82 (25.7)

 Partial remission

19 (10.5)

26 (11.3)

47 (19.5)

70 (26.6)

55 (18.9)

83 (26.0)

 Complete remission

26 (14.4)

48 (20.9)

37 (15.4)

37 (14.1)

36 (12.4)

36 (11.3)

 Progressive

65 (35.9)

80 (34.8)

85 (35.3)

94 (35.7)

102 (35.1)

114 (35.7)

Recent oncological treatment (< 3 months)

       

 Antitumoral drug treatment

69 (38.5)

98 (42.8)

115 (47.7)

141 (53.6)

163 (56.0)

170 (53.3)

0.001

 Immunotherapy and targeted therapy

8 (4.4)

18 (7.8)

17 (7.1)

35 (13.3)

37 (12.7)

60 (18.8)

 < 0.001

 First-line treatment

45 (25.0)

58 (25.2)

63 (26.1)

4 (28.1)

91 (31.3)

83 (26.0)

0.577

 Radiotherapy

13 (7.2)

17 (7.4)

16 (6.7)

22 (8.4)

17 (5.8)

22 (6.9)

0.543

 Surgery

30 (16.8)

38 (16.5)

35 (14.5)

37 (14.1)

25 (8.6)

47 (14.7)

0.184

  1. a Available for 1510 (99%) patients
  2. Continuous variables are expressed as median (interquartile range) and categorical variables as counts (percentages)