Characteristics | Alive | Deceased | p | Multivariate analysis | |
---|---|---|---|---|---|
(n = 424) | (n = 510) | Cause-specific hazard [95% CI] | p | ||
Age (years) | 67 [59–74] | 68 [60–76] | 0.18 | 1.008 [1.007–1.012] | 0.03 |
Male gender | 248 (58.5) | 297 (58.2) | 0.4 | ||
ICU admission | |||||
2007–2012 | 174 (42.1) | 210 (42.2) | 0.54 | ||
2013–2018 | 250 (58.1) | 300 (58.8) | |||
Type of cancer | < 0.001 | ||||
Lung | 65 (15.3) | 139 (27.3) | |||
Gastrointestinal | 116 (27.4) | 141 (27.7) | |||
Urologic | 103 (24.3) | 109 (21.4) | |||
Cutaneous | 7 (1.7) | 14 (2.8) | |||
Breast | 48 (11.3) | 26 (5.1) | |||
Lung cancer | 65 (15.3) | 139 (27.3) | < 0.001 | 1.44 [1.16–1.78] | < 0.001 |
Non-lung cancer | 359 (84.7) | 371 (72.7) | – | – | |
Stage | < 0.001 | ||||
Localized | 181 (42.7) | 73 (14.3) | – | – | |
Advanced | 99 (23.3) | 104 (20.4) | – | – | |
Metastatic | 141 (33.3) | 329 (64.5) | 1.90 [1.53–2.37] | < 0.001 | |
Status | < 0.001 | ||||
Newly diagnosed | 112 (26.4) | 164 (32.2) | – | – | |
Partial remission | 118 (27.8) | 80 (15.7) | – | – | |
Complete remission | 116 (27.4) | 34 (6.7) | – | – | |
In progression | 78 (18.4) | 232 (45.5) | 1.39 [1.13–1.72] | 0.002 | |
Treatment in the past 3 months | |||||
Chemotherapy | 172 (40.5) | 272 (53.3) | < 0.001 | – | – |
Surgery | 93 (21.9) | 55 (10.8) | 1.000 | 0.78 [0.57–1.05] | 0.11 |
Immunotherapy/targeted therapy | 32 (7.5) | 72 (14.1) | 0.002 | – | – |
SOFA score | 5 [3.75–7] | 5 [4–7] | 0.379 | 1.03 [0.99–1.06] a | 0.05 |
Organ failure supports | |||||
Invasive mechanical ventilation | 121 (28.5) | 140 (27.5) | 0.519 | – | – |
Non-invasive mechanical ventilation | 54 (12.7) | 59 (11.6) | 0.657 | – | – |
Inotropes/vasopressors | 91 (21.5) | 111 (21.8) | 0.975 | – | – |
Renal replacement therapy | 49 (11.6) | 64 (12.5) | 0.717 | – | – |
Admission patterns | |||||
Non-specific complications | 292 (68.9) | 288 (56.5) | < 0.001 | – | – |
Specific complications | 67 (15.8) | 178 (34.9) | < 0.001 | 1.75 [1.43–2.15] | < 0.001 |
Adverse event complications | 65 (15.3) | 44 (8.6) | 0.002 | – | – |
Drug-related adverse event | 17 (4.0) | 24 (4.7) | 0.721 | – | – |
Procedural adverse event | 48 (11.3) | 20 (3.9) | < 0.001 | – | – |
Decision to forgo life-sustaining therapy | 11 (2.6) | 120 (23.5) | < 0.001 | 3.21 [2.54–4.06] | < 0.001 |