Duration of invasive mechanical ventilation prior to extracorporeal membrane oxygenation is not associated with survival in acute respiratory distress syndrome caused by coronavirus disease 2019

Annals of Intensive Care

Table 4 Effect of pre-ECMO IMV duration on ICU mortality in all patients with confounders age, modified SOFA, comorbidities, and modified RESP score

	Estimate (95%C.I.)	OR (95%C.I.)	p value
Intercept	−12.141 [−18.812, −6.632]	.	0.0001
Pre-ECMO IMV duration	−0.044 [−0.116, 0.021]	0.957 [0.89, 1.022]	0.1988
Age	0.174 [0.098, 0.267]	1.19 [1.103, 1.022]	< 0.001
SOFA score excluding PaO₂/FiO₂	0.403 [0.193, 0.663]	1.496 [1.213, 1.022]	0.0007
RESP score excluding age and IMV	−0.917 [−1.823, −0.099]	0.4 [0.162, 1.022]	0.0346
Underlying pulmonary disease	1.412 [0.033, 2.914]	4.103 [1.033, 1.022]	0.0517

IMV invasive mechanical ventilation, ECMO extracorporeal membrane oxygenation, SOFA Sequential Organ Failure Assessment, PaO₂ partial pressure of arterial oxygen, FiO₂ fraction of inspired oxygen, RESP respiratory ECMO survival prediction, ICU intensive care unit