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Table 1 Baseline and ICU admission characteristics according to ventilator type in patients with acute respiratory distress syndrome due to COVID-19

From: Association of ventilator type with hospital mortality in critically ill patients with SARS-CoV2 infection: a prospective study

Variables All patients
n = 189
ICU ventilator
n = 143 (75.7)
Transport ventilator
n = 46 (24.3)
P value N missinga
Demographic characteristics     
 Age (years) 65 [57–73] 65 [56–74] 65 [60–73] 0.90  
 Male sex 140 (74.1) 112 (78.3) 28 (60.9) 0.03  
 Active smoking 11 (6.0) 9 (6.4) 2 (4.4) 1.00 4
Comorbidities      
 Coronary artery disease 18 (9.5) 14 (9.8) 4 (8.7) 1.00  
 Treated arterial hypertension 87 (46.0) 69 (48.3) 18 (39.1) 0.31  
 Diabetes mellitus 55 (29.1) 45 (31.5) 10 (21.7) 0.26  
 Immunodeficiency 18 (9.5) 15 (10.5) 3 (6.5) 0.57  
 Obesity (BMI ≥ 30 kg/m2) 70 (37.2) 56 (39.4) 14 (30.4) 0.30 1
 Asthma 15 (7.9) 10 (7.0) 5 (10.9) 0.37  
 COPD 10 (5.3) 8 (5.6) 2 (4.4) 1.00  
 Bronchectasis 2 (1.1) 2 (1.4) 0 (0.0) 1.00  
Characteristics at ICU admission      
 Epidemic COVID-19 wave     0.23  
  Wave 1 82 (43.4) 66 (46.2) 16 (34.8)   
  Wave 2 37 (19.6) 29 (20.3) 8 (17.4)   
  Wave 3 70 (37.0) 48 (33.6) 22 (47.8)   
 SAPS II 40 [34–49] 41 [34–50] 40 [35–45] 0.45  
 Day 1, total SOFA scoreb 6 [4–7] 6 [4–7] 6 [4–7] 0.72 1
 Respiratory SOFA score 3 [3, 4] 3 [3, 4] 3 [-4] 0.18  
 Cardiovascular SOFA score 3 [0–3] 3 [0–3] 3 [0–3] 0.96  
 Renal SOFA score 0 [0–0] 0 [0–1] 0 [0–0] 0.28 1
 Neurological SOFA score 0 [0–0] 0 [0–0] 0 [0–0] 0.89  
 Hepatic SOFA score 0 [0–0] 0 [0–0] 0 [0–0] 0.13 1
 Coagulation SOFA score 0 [0–0] 0 [0–0] 0 [0–1] 0.28 1
 Time from symptom onset to ICU admission (days) 9 [6–11] 8 [6–12] 9 [6–11] 0.84 1
 Time from hospitalization to ICU admission (days) 1 [0–3] 1 [0–3] 2 [0–4] 0.04 1
 Pulmonary co-infection at ICU admission 16 (8.5) 13 (9.1) 3 (6.5) 0.70  
 Oxygen requirements at ICU admission (L/min) 15 [15–15] 15 [15–15] 15 [13–15] 0.71 4
Laboratory tests at ICU admission      
 Lactate (mmol/L) 1.5 [1.2–1.9] 1.6 [1.3–2.0] 1.4 [1.2–1.7] 0.03 1
 LDH (IU/L) 724 [532–915] 759 [609–1002] 580 [464–763]  < 0.001 3
 Lymphocytes (G/L) 0.66 [0.45–0.95] 0.70 [0.45–1.00] 0.62 [0.43–0.84] 0.17 6
 C-reactive protein (mg/L) 167 [94–242] 170 [95–245] 147 [86–200] 0.25 23
 Procalcitonin (ng/mL) 0.4 [0.2–1.1] 0.4 [0.2–1.3] 0.3 [0.2–0.7] 0.16 26
 d-dimers (ng/mL) 1525 [883–2550] 1750 [970–2650] 1090 [770–1730] 0.02 27
 Creatinine (µmol/L) 73 [60–98] 78 [62–101] 66 [53–88] 0.02 1
 Troponin (ng/mL) 0.01 [0.01–0.02] 0.01 [0.01–0.03] 0.01 [0.01–0.02] 0.44 25
 NT-proBNP (pg/mL) 383 [156–973] 473 [188–1021] 311 [143–670] 0.27 70
  1. Data are Presented as N (%) or median [interquartile range]
  2. BMI body mass index, COPD chronic obstructive pulmonary disease, ICU intensive care unit, SAPS II Simplified Acute Physiology Score II, SOFA sepsis-related organ failure assessment, LDH lactate dehydrogenase, CRP NT-proBNP: NT-pro B-type natriuretic peptide
  3. aNumber of missing observations, unless Ø
  4. bSix organs or systems are assessed, each receiving 0 (no dysfunction) to 4 points (more severe dysfunction). The sum of scores ranges from 0 to 24; higher scores indicate more severe disease