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Table 2 ICU management and outcomes according to ventilator type in patients with COVID-19-related acute respiratory distress syndrome

From: Association of ventilator type with hospital mortality in critically ill patients with SARS-CoV2 infection: a prospective study

Variables All patients
n = 189
ICU ventilator
n = 143 (75.7)
Transport ventilator
n = 46 (24.3)
P value N missinga
ICU management      
 High-flow nasal oxygen 112 (59.3) 80 (55.9) 32 (69.6) 0.12  
 Non-invasive ventilation 48 (25.4) 33 (23.1) 15 (32.6) 0.24  
 Last PaO2/FiO2 ratio before intubation 89 [71–123] 89 [72–123] 84 [69–113] 0.52 28
Ventilatory settings, first day of ARDS      
 First PaO2/FiO2 ratio under invasive MV 139 [99–178] 139 [99–178] 126 [98–174] 0.36 2
 Corresponding first FiO2 under invasive MV 1.0 [0.8–1.0] 1.0 [0.8–1.0] 0.9 [0.7–1.0] 0.02 2
 Tidal volume (mL/kg PBW) 6.0 [5.9–6.2] 6.0 [5.9–6.2] 6.0 [6.0–6.1] 0.64 3
 Set PEEP, cm H2O 12 [10–12] 12 [10–12] 12 [10–12] 0.69 2
 Plateau pressure (PPLAT, cm H2O) 23 [21–25] 23 [21–25] 22 [20–24] 0.23 25
 Driving pressure, cm H2O 10 [9–12] 11 [9–13] 10 [9–11] 0.10 25
 Time from ICU admission to intubation (days) 0 [0–1] 0 [0–1] 0 [0–1] 0.34 1
 Prone positioning 133 (70.4) 99 (69.2) 34 (73.9) 0.58  
 Number of prone position sessions 4 [2–7] 4 [2–8] 4 [2–6] 0.43  
 Inhaled nitric oxide 52 (27.5) 42 (29.4) 10 (21.7) 0.35  
 ECMO 10 (5.3) 10 (7.0) 0 (0.0) 0.12  
 Ventilator-associated pneumonia 110 (58.2) 80 (55.9) 30 (65.2) 0.31  
 Weaning failure (≥ 2 orotracheal intubations) 27 (14.3) 17 (11.9) 10 (21.7) 0.14  
 Tracheostomy 27 (14.3) 20 (14.0) 7 (15.2) 0.81  
 Need for vasoactive drugs in the ICU 176 (93.1) 134 (93.7) 42 (91.3) 0.52  
 Need for renal replacement therapy in the ICU 28 (14.8) 25 (17.5) 3 (6.5) 0.09  
 Dexamethasone initiated at ICU admission 107 (56.6) 77 (53.9) 30 (65.2) 0.23  
 Rescue dexamethasone for persistent ARDS 38 (20.1) 30 (21.0) 8 (17.4) 0.68  
Outcomes      
 Duration of invasive MV, days 19 [11–33] 18 [11–32] 21 [13–37] 0.39  
 ICU length of stay (days) 24 [15–41] 24 [14–40] 27 [15–44] 0.44  
 ICU mortality 60 (31.8) 47 (32.9) 13 (28.3) 0.59  
 Post-ICU hospital length of stay (days) 10 [7–15] 11 [8–16] 9 [7–12] 0.10  
 Hospital mortality 61 (32.3) 48 (33.6) 13 (28.3) 0.59  
 Rehabilitation-unit length of stay (days) 27 [17–41] 27 [17–41] 31 [21–42] 0.68  
 Day-90 mortality 63 (33.3) 50 (35.0) 13 (28.3) 0.47  
  1. Data are presented as N (%) or Median [interquartile range]
  2. ICU intensive care unit, PaO2/FiO2 partial pressure of oxygen to fraction of inspired oxygen, ARDS acute respiratory distress syndrome, PBW predicted body weight, MV mechanical ventilation, PEEP positive end-expiratory pressure, ECMO extracorporeal membrane oxygenation, ARDS acute respiratory distress syndrome
  3. aNumber of missing observations, unless Ø