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Table 1 Characteristics of included studies

From: Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies

Study Country Period Study design Inclusion criteria ECMO group of children with underlying malignancies
Lindén et al. 1999 [19] Sweden NR Retro, single center Underlying malignancy and PCP pneumonia 4
Gupta et al. 2008 [20] ELSO registry 1985–2004 Retro, multicenter ELSO registry Immunocompromised condition and respiratory failure as indication for ECMO
Age 30 days–19 yrs
60
Gow et al. 2009 [21] ELSO registry 1992–2007 Retro, multicenter ELSO registry Underlying malignancy
Age < 21 yrs
107
Meister et al. 2009 [22] Austria NR Retro, single center Leukemia 4
Di Nardo et al. 2014 [23] ELSO registry 1991–2012 Retro, multicenter ELSO registry HSCT patients
Age < 18 yrs
15
Smith et al. 2016 [24] Australia 1993–2014 Retro, single center Pediatric cancer patients with neutropenic sepsis 9
Bailly et al. 2017 [25] ELSO registry 2001–2013 Retro, multicenter ELSO registry ECMO for respiratory failure due to a primary pulmonary diagnosis
Age 7 days–18 yrs
161
Cortina et al. 2018 [26] Austria 2004–2007 Retro, single center Leukemia 9
Maue et al. 2019 [27] USA 2011–2016 Retro, single center Pediatric oncology and/or HSCT patients 5
Steppan et al. 2020 [28] USA 2011–2018 Retro, multicenter PEDECOR registry Pediatric oncology and/or HSCT patients 16
Ranta et al. 2020 [29] Sweden 2008–2016 Retro, multicenter Hematological malignancies 12
Coleman et al. 2020 [30] USA 2004–2013 Retro, multicenter PHIS registry Underlying malignancy, genetic disorders or high-risk congenital heart disease 200
Friedman et al. 2020 [31] USA 2011–2016 Retro, multicenter Patients requiring VV-ECMO
Age 14 days-18 yrs
23
  1. ECMO extracorporeal membrane oxygenation, ELSO registry extracorporeal life support organization registry including > 145 centers worldwide, HSCT hematopoietic stem cell transplantation, PCP Pneumocystis carinii pneumonia, Retro retrospective, yrs year