| |
Early CAG group (N = 1148)
|
Deferred CAG/no CAG group (N = 1227)
|
p-value
|
|---|
|
Targeted temperature management
|
670/849 (78.9)
|
570/709 (80.4)
|
0.47
|
|
Hypotension
|
244/554 (44.0)
|
293/692 (42.3)
|
0.55
|
|
Use of inotropic or vasopressors
|
319/512 (62.3)
|
422/688 (61.3)
|
0.73
|
|
Use of intra-aortic balloon pump
|
96/993 (9.7)
|
40/1026 (3.9)
|
< 0.001
|
|
Heart failure < 45%
|
200/496 (40.3)
|
134/313 (42.8)
|
0.48
|
|
Need for renal replacement therapy
|
34/839 (4.1)
|
42/701 (6.0)
|
0.08
|
|
Major bleedinga
|
15/347 (4.3)
|
23/357 (6.4)
|
0.21
|
|
CAG performed
|
1148 (100.0)
|
600/1227 (48.9)
|
< 0.001
|
|
PCI performed
|
205/248 (82.7)
|
129/356 (36.2)
|
< 0.001
|
|
CABG
|
8/292 (2.7)
|
9/392 (2.3)
|
0.71
|
|
Laboratory values
|
|
Lowest pH
|
7.2 [7.1–7.3]
|
7.2 [7.0–7.3]
|
0.003
|
|
Peak lactate, mmol/L
|
5.5 [3.4–9.1]
|
6.0 [3.4–9.5]
|
0.38
|
|
Peak CRP, mg/L
|
105 [30–201]
|
122 [61–200]
|
0.06
|
|
Peak leukocytes, ·109/L
|
18.4 [14.3–24.2]
|
17.6 [13.9–23.2]
|
0.34
|
|
Peak CK, U/L
|
1604 [629–4421]
|
828 [296–2411]
|
< 0.001
|
|
Survival at hospital discharge
|
544/765 (71.1)
|
596/850 (70.1)
|
0.66
|
- All data are expressed in proportions of the population with known data and percentages (%). Brackets are classified as median and interquartile ranges (IQR)
- CAG coronary angiography, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, CRP C-reactive protein, CK creatine kinase
- aMajor bleeding was scored using BARC classification scores ≥ 3, ranging from bleeding that is not actionable to fatal bleedings
