| |
Cutoff value
|
Sensitivity (%)
|
Specificity (%)
|
PPV (%)
|
NPV (%)
|
|---|
|
[TIMP-2]*[IGFBP7] day 0 [(ng/mL)2/1000]
|
1.05
|
82.3 (67.4, 93.8)
|
76.9 (72.4, 88.5)
|
65.0 (43.2, 78.6)
|
88.5 (76.3, 95.8)
|
|
Clinical risk prediction model
|
0.436
|
77.1 (62.5, 92.3)
|
76.4 (60.2, 91.0)
|
67.5 (50.3, 81.4)
|
84.8 (65.3, 94.3)
|
|
[(TIMP-2)*(IGFBP7) day 0]—clinical risk prediction model
|
0.290
|
88.8 (72.9, 98.7)
|
86.2 (70.4, 97.3)
|
80.0 (65.9, 92.5)
|
92.6 (80.8, 100.0)
|
- TIMP-2 tissue inhibitor of metalloproteinases-2, IGFBP-7 insulin-like growth factor-binding protein 7, PPV positive predictive value, NPV negative predictive value
