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Annals of Intensive Care

Table 5 Predictive accuracy of the biomarkers for non-recovery

From: Cell cycle arrest biomarkers for predicting renal recovery from acute kidney injury: a prospective validation study

 

Cutoff value

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

[TIMP-2]*[IGFBP7] day 0 [(ng/mL)2/1000]

1.05

82.3 (67.4, 93.8)

76.9 (72.4, 88.5)

65.0 (43.2, 78.6)

88.5 (76.3, 95.8)

Clinical risk prediction model

0.436

77.1 (62.5, 92.3)

76.4 (60.2, 91.0)

67.5 (50.3, 81.4)

84.8 (65.3, 94.3)

[(TIMP-2)*(IGFBP7) day 0]—clinical risk prediction model

0.290

88.8 (72.9, 98.7)

86.2 (70.4, 97.3)

80.0 (65.9, 92.5)

92.6 (80.8, 100.0)

  1. TIMP-2 tissue inhibitor of metalloproteinases-2, IGFBP-7 insulin-like growth factor-binding protein 7, PPV positive predictive value, NPV negative predictive value
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