Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study

Annals of Intensive Care

Table 2 Multivariable logistic regression model for ICU admission in the American cohort^a

Variable	Odds ratio (95% CI)	P value	Coefficient
Female	0.94 (0.89–0.99)	0.046	− 0.059
Age
90 and above 86–89 83–85 80–82	0.82 (0.75–0.89) 0.85 (0.79–0.92) 0.96 (0.88–1.04) 1	< 0.001 < 0.001 0.27 Reference	− 0.202 − 0.161 − 0.044 Reference
LAPS score
38 and higher 24–37 15–23 6–14 0–5	14.65 (12.88–16.65) 3.43 (3.01–3.91) 2.03 (1.77–2.32) 1.35 (1.16–1.58) 1	< 0.001 < 0.001 < 0.001 < 0.001 Reference	2.684 1.234 0.707 0.304 Reference
Charlson comorbidity index
7 and higher 6 0–5	0.92 (0.85–1.002) 0.86 (0.8–0.92) 1	0.05 < 0.001 Reference	0.079− − 0.151 Reference
Primary diagnosis^b
Acute respiratory failure	21.61 (12.53–37.25)	< 0.001	3.073
Sepsis	4.87 (4.27–5.55)	< 0.001	1.583
Stroke and TIA	2.25 (1.91–2.64)	< 0.001	0.81
DVT PE	1.45 (1.11–1.91)	0.01	0.374
Acute pancreatitis	0.88 (0.59–1.32)	0.55	− 0.123
Pneumonia	0.85 (0.73–0.99)	0.03	− 0.165
Cholecystitis/cholangitis	0.81 (0.6–1.11)	0.2	− 0.205
Atrial fibrillation/flutter	0.73 (0.58–0.92)	0.01	− 0.313
Heart failure	0.72 (0.64–0.81)	< 0.001	− 0.332
Femoral fracture	0.55 (0.45–0.66)	< 0.001	− 0.602
Dyspnea	0.21 (0.08–0.53)	< 0.001	− 1.557
Fever	0.17 (0.06–0.47)	< 0.001	− 1.779
UTI	0.17 (0.13–0.23)	< 0.001	− 1.756
Syncope	0.09 (0.04–0.18)	< 0.001	− 2.403

LAPS laboratory-based Acute Physiology Score, ICU intensive care unit, URTI upper respiratory tract infection, DVT PE deep vein thrombosis and pulmonary embolism, TIA transient ischemic attack, COPD chronic obstructive pulmonary disease, UTI urinary tract infection
^aThe model has c-statistic of 0.8, demonstrating good discrimination
^bDiagnoses that were included in the model but do not appear in the table: abdominal pain, URTI, anemia, cellulitis, dizziness, hyponatremia, COPD