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Table 1 Clinical characteristics and outcomes of patients having acute respiratory failure with or without pendelluft

From: Prevalence and prognosis of respiratory pendelluft phenomenon in mechanically ventilated ICU patients with acute respiratory failure: a retrospective cohort study

  All patients
(n = 200)
No pendelluft
(n = 139)
Pendelluft
(n = 61)
p value
Age, years 62 (51, 69) 62 (51, 68) 62 (50, 73) 0.549
Female gender, n (%) 65 (32%) 44 (32%) 21 (34%) 0.825
Predicted body weight, kg 64.0 (56.2, 68.5) 64.0 (54.1, 68.5) 64.9 (56.8, 69.4) 0.290
APACHE II score 16 (13, 20) 16 (13, 20) 17 (14, 23) 0.153
Respiratory parameters
 Spontaneous breathing, n (%) 94 (47%) 55 (40%) 39 (64%) 0.002
 Tidal volume, mL 428 (396, 501) 430 (398, 500) 421 (390, 510) 0.810
 Respiratory rate, minute−1 17 (15, 19) 16 (15, 18) 18 (16, 21) 0.002
 PEEP, cmH2O 7 (5, 8) 7 (5, 8) 6 (5, 8) 0.152
Arterial blood gas
 PaO2/FiO2 ratio, mmHg 200 (164, 246) 204 (167, 249) 194 (151, 239) 0.225
 pH 7.4 (7.4, 7.5) 7.4 (7.4, 7.5) 7.4 (7.4, 7.5) 0.763
 PaCO2, mmHg 40.8 (37.0, 43.9) 41.0 (37.6, 44.0) 39.4 (36.0, 42.4) 0.189
 Ventilatory ratio 1.3 (1.2, 1.5) 1.3 (1.2, 1.5) 1.4 (1.2, 1.6) 0.170
EIT parameters
 Dorsal ventilation, % 41 (32, 47) 41 (32, 48) 41 (32, 47) 0.984
 Defect Score, n (%)     0.042
  0 88 (44%) 68 (49%) 20 (33%)  
  1 61 (30%) 42 (30%) 19 (31%)  
  ≥ 2 51 (26%) 29 (21%) 22 (36%)  
  GI index 0.36 (0.34, 0.38) 0.36 (0.34, 0.37) 0.37 (0.34, 0.39) 0.023
  Pendelluft amplitude, % 1.4 (0.7, 3.5) 0.9 (0.5, 1.6) 6.4 (3.9, 13.3)  < 0.001
Outcome
 MV duration, days 5 (3, 8) 4 (2, 7) 6 (3, 8) 0.052
 ICU length of stay, days 7 (5, 13) 7 (4, 11) 10 (6, 14) 0.022
 14-day ventilator-free days 9 (5, 11) 10 (6, 12) 8 (1, 10) 0.015
 ICU mortality, n (%) 23 (12%) 13 (9%) 10 (16%) 0.151
  1. Data are presented as median (lower, upper quartile) unless otherwise specified
  2. APACHE Acute Physiology and Chronic Health Evaluation, PEEP positive end-expiratory pressure, EIT electrical impedance tomography, GI global inhomogeneity, MV mechanical ventilation, ICU intensive care unit