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Table 3 Logistic regression analyses for factors associated with modified Rankin Scale scores of 0–2 at year-1 after ICU discharge

From: Neurologic outcome of VZV encephalitis one year after ICU admission: a multicenter cohort study

Variables

Univariate analysis

Multivariable analysis

OR [95% CI]

p-value

OR [95% CI]

p-value

Age, per year

0.93 [0.89–0.97]

0.0006

0.92 [0.88–0.97]

0.01

GCS at ICU admission, per point

1.13 [0.97–1.33]

0.12

  

Focalization sign at ICU admission

1.93 [0.58–6.39]

0.27

  

Seizures

1.46 [0.45–4.69]

0.52

  

Status epilepticus

0.84 [0.21–3.36]

0.81

  

SOFA at day 1, per point

0.88 [0.75–1.03]

0.1

  

Maximal temperature at ICU admission, per degree

1.09 [0.65–1.82]

0.74

  

Underlying immunosuppression

0.19 [0.05–0.79]

0.019

0.26 [0.04–1.59]

0.13

CSF elements, per element

1.00 [0.99–1.00]

0.40

  

CSF protein level, per g/L

0.65 [0.39–1.09]

0.09

  

Invasive mechanical ventilation

0.22 [0.05–1.04]

0.05

0.09 [0.01–0.84]

0.03

Renal replacement therapy

0.83 [0.23–2.99]

0.78

  

Vasopressors

0.35 [0.10–1.22]

0.09

  

Vasculitis on brain MRI

0.44 [0.076–2.576]

0.35

  

Time from the onset of neurological symptoms to acyclovir, days

0.99 [0.91–1.08]

0.74

  

High dose of steroids

0.71 [0.06–8.87]

0.78

  
  1. CSF, cerebrospinal fluid; GCS, Glasgow Coma Scale; ICU, intensive care unit; MRI, magnetic resonance imaging; SOFA, Sequential Organ Failure Assessment