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Table 3 Logistic regression analyses for factors associated with modified Rankin Scale scores of 0–2 at year-1 after ICU discharge

From: Neurologic outcome of VZV encephalitis one year after ICU admission: a multicenter cohort study

Variables Univariate analysis Multivariable analysis
OR [95% CI] p-value OR [95% CI] p-value
Age, per year 0.93 [0.89–0.97] 0.0006 0.92 [0.88–0.97] 0.01
GCS at ICU admission, per point 1.13 [0.97–1.33] 0.12   
Focalization sign at ICU admission 1.93 [0.58–6.39] 0.27   
Seizures 1.46 [0.45–4.69] 0.52   
Status epilepticus 0.84 [0.21–3.36] 0.81   
SOFA at day 1, per point 0.88 [0.75–1.03] 0.1   
Maximal temperature at ICU admission, per degree 1.09 [0.65–1.82] 0.74   
Underlying immunosuppression 0.19 [0.05–0.79] 0.019 0.26 [0.04–1.59] 0.13
CSF elements, per element 1.00 [0.99–1.00] 0.40   
CSF protein level, per g/L 0.65 [0.39–1.09] 0.09   
Invasive mechanical ventilation 0.22 [0.05–1.04] 0.05 0.09 [0.01–0.84] 0.03
Renal replacement therapy 0.83 [0.23–2.99] 0.78   
Vasopressors 0.35 [0.10–1.22] 0.09   
Vasculitis on brain MRI 0.44 [0.076–2.576] 0.35   
Time from the onset of neurological symptoms to acyclovir, days 0.99 [0.91–1.08] 0.74   
High dose of steroids 0.71 [0.06–8.87] 0.78   
  1. CSF, cerebrospinal fluid; GCS, Glasgow Coma Scale; ICU, intensive care unit; MRI, magnetic resonance imaging; SOFA, Sequential Organ Failure Assessment