From: Neurologic outcome of VZV encephalitis one year after ICU admission: a multicenter cohort study
Variables | Univariate analysis | Multivariable analysis | ||
---|---|---|---|---|
OR [95% CI] | p-value | OR [95% CI] | p-value | |
Age, per year | 0.93 [0.89–0.97] | 0.0006 | 0.92 [0.88–0.97] | 0.01 |
GCS at ICU admission, per point | 1.13 [0.97–1.33] | 0.12 | ||
Focalization sign at ICU admission | 1.93 [0.58–6.39] | 0.27 | ||
Seizures | 1.46 [0.45–4.69] | 0.52 | ||
Status epilepticus | 0.84 [0.21–3.36] | 0.81 | ||
SOFA at day 1, per point | 0.88 [0.75–1.03] | 0.1 | ||
Maximal temperature at ICU admission, per degree | 1.09 [0.65–1.82] | 0.74 | ||
Underlying immunosuppression | 0.19 [0.05–0.79] | 0.019 | 0.26 [0.04–1.59] | 0.13 |
CSF elements, per element | 1.00 [0.99–1.00] | 0.40 | ||
CSF protein level, per g/L | 0.65 [0.39–1.09] | 0.09 | ||
Invasive mechanical ventilation | 0.22 [0.05–1.04] | 0.05 | 0.09 [0.01–0.84] | 0.03 |
Renal replacement therapy | 0.83 [0.23–2.99] | 0.78 | ||
Vasopressors | 0.35 [0.10–1.22] | 0.09 | ||
Vasculitis on brain MRI | 0.44 [0.076–2.576] | 0.35 | ||
Time from the onset of neurological symptoms to acyclovir, days | 0.99 [0.91–1.08] | 0.74 | ||
High dose of steroids | 0.71 [0.06–8.87] | 0.78 |