The ability of Oxygen Reserve Index® to detect hyperoxia in critically ill patients

Annals of Intensive Care

Table 4 Diagnostic performance of ORI and SpO₂ to detect PaO₂ > 100 mmHg and PaO₂ > 120 mmHg

Parameter	Hyperoxia threshold	AUROC [CI95%]	Youden index	Best threshold	Sensitivity [CI95%]	Specificity [CI95%]	PPV [CI95%]	NPV [CI95%]
ORI	100 mmHg	0.567 [0.566–0.569]	0.140	0.005	0.233 [0.230–0.235]	0.907 [0.907–0.910]	0.567 [0.563–0.571]	0.696 [0.694–0.698]
SpO₂	100 mmHg	0.771 [0.770–0.773]	0.416	97.5	0.715 [0.712–0.718]	0.700 [0.697–0.703]	0.555 [0.552–0.558]	0.826 [0.824–0.828]
ORI	> 120 mmHg	0.584 [0.582–0.586]	0.182	0.065	0.289 [0.285–0.294]	0.892 [0.891–0.893]	0.257 [0.254–0.260]	0.906 [0.905–0.907]
SpO2	> 120 mmHg	0.764 [0.762–0.766]	0.420	97.5	0.799 [0.795–0.803]	0.623 [0.620–0.626]	0.218 [0.216–0.220]	0.959 [0.958–0.960]

AUROC area under the receiver operating characteristic curve, NPV negative predictive value, ORI Oxygen Reserve Index, PPV positive predictive value, SpO₂: pulse oximetry