Association of immediate reinsertion of new catheters with subsequent mortality among patients with suspected catheter infection: a cohort study

Annals of Intensive Care

Table 2 Sensitivity and subgroup analyses of incidence and population-attributable mortality fraction of immediate reinsertion of new catheters (IRINC) in patients ^a

Characteristic	Suspected (n = 1238)	IRINC (n = 877)	Death (n = 202)	Day 30-Attributable Mortality Hazard Ratios (95% CI)	P-value
Cause ^b
Bloodstream Infection, n (%)	298 (24.1)	232 (26.4)	52 (25.7)	1.081 (0.964–1.213)	0.184
Pneumonia, n (%)	603 (48.7)	433 (49.4)	109 (54.0)	1.128 (1.031–1.233)	0.008
Other Infection, n (%)	337 (27.2)	212 (24.2)	41 (20.3)	1.690 (0.928–3.076)	0.086
Year ^c
2009–2016, n (%)	695 (56.1)	582 (66.4)	131 (64.9)	1.100 (1.040–1.163)	0.001
2017–2021, n (%)	543 (43.9)	295 (33.6)	71(35.1)	1.213 (1.049–1.402)	0.009

^a A population-attributable mortality fraction base on Cox proportional hazards models, which using the same covariable, we attempt to evaluate the proportion of cases of deaths that could be prevented if the influence of IRINC was removed
^b Bloodstream infection as a stratification variable including catheter-related bloodstream infection and bacteremia without catheter colonization, regardless of complications with or without other infections; Pneumonia as a stratification variable only was confirmed pneumonia in patients without combined other infections; Other infection as a stratification variable including fewer cases of infection and an unknown source of infection
^c 2009–2016 as a stratification variable because it is the rate of IRINC more than 70%, or 2017–2021 as a stratification variable because it is the rate of IRINC less than 70%, to identify the risk of attributable mortality