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Table 4 Multivariate logistic regression model of factors associated with the ICU mortality in all patients

From: Presence of comorbidities alters management and worsens outcome of patients with acute respiratory distress syndrome: insights from the LUNG SAFE study

Variable

OR

95% CI

p

Age

1.02

1.01–1.03

 < 0.001

BMI

0.98

0.97–1.00

0.022

Comorbidity

   

 Chronic respiratory impairment

0.98

0.78–1.23

0.839

 Congestive heart failure

1.42

1.07–1.90

0.016

 Chronic renal failure

0.97

0.72–1.31

0.858

 Chronic liver failure

3.35

2.11–5.34

 < 0.001

 Immune incompetence

1.96

1.58–2.42

 < 0.001

 Diabetes

0.91

0.73–1.15

0.440

Medical admission

1.51

1.21–1.89

 < 0.001

No longer fulfill ARDS criteria after 24 h

0.72

0.56–0.92

0.010

Adjusted non-respiratory SOFA

1.11

1.08–1.14

 < 0.001

pH

0.74

0.67–0.81

 < 0.001

PaO2/FiO2

0.98

0.97–1.00

0.013

paCO2

0.99

0.98–1.00

0.019

PEEP

0.96

0.93–0.99

0.005

Total respiratory rate

1.03

1.02–1.04

 < 0.001

No use of adjunctive measures within 28-day follow-up (Ref. Use of adjuncts)

0.64

0.52–0.77

 < 0.001

High-income RW (vs Europe)

0.71

0.57–0.89

0.003

Middle-income countries (vs Europe)

1.62

1.29–2.04

 < 0.001

  1. Sample size n = 2611
  2. BMI body mass index, SOFA Sequential Organ Failure Assessment, PEEP positive end-expiratory pressure, RR respiratory rate, RW rest of the world