Fig. 3From: Does the cytokine adsorber CytoSorb® reduce vancomycin exposure in critically ill patients with sepsis or septic shock? a prospective observational studyPredicted (n = 3000) vancomycin pharmacokinetic plasma profile during continuous infusion. Left: without CytoSorb®. Middle: with CytoSorb® installation after 10 h and no additional vancomycin dose. Right: with CytoSorb® installation after 10 h and an additional vancomycin dose of 500 mg over 2 h. For all scenarios, a continuous infusion of 46 mg/h was administered. Black line: median prediction, Green shade: 50% prediction interval, red vertical line: insertion of the CytoSorb®Back to article page