From: Corporeal rehabilitation to manage acute stress in critically ill patients
Parameter | N | All patients (n = 287) | Non-responders (n = 99) | Responders (n = 188) | p value |
---|---|---|---|---|---|
Patients’ characteristics | |||||
 Female gender | 287 | 164 (57%) | 44 (44%) | 120 (64%) | 0.002 |
 Age (years) | 287 | 59 [37–70] | 63 [48–72] | 55 [36–70] | 0.047 |
 Body mass index (kg/m2) | 257 | 25 [21–29] | 24 [21–28] | 24 [21–29] | 0.904 |
Past medical history | |||||
 Respiratory disease | 287 | 101 (35%) | 34 (34%) | 67 (36%) | 0.827 |
 Cardiac disease | 287 | 135 (47%) | 55 (56%) | 80 (43%) | 0.036 |
 Neurological disease | 287 | 35 (12%) | 10 (10%) | 25 (13%) | 0.431 |
 Cirrhosis | 287 | 7 (2%) | 3 (3%) | 4 (2%) | 0.696 |
 Cancer | 287 | 44 (15%) | 19 (19%) | 25 (13%) | 0.188 |
 Blood cancers | 287 | 26 (9%) | 14 (14%) | 12 (6%) | 0.030 |
 Sickle cell disease | 287 | 65 (23%) | 16 (16%) | 49 (26%) | 0.057 |
 Chronic kidney failure | 287 | 12 (4%) | 4 (4%) | 8 (4%) | > 0.99 |
 Psychiatric disease | 287 | 30 (11%) | 12 (12%) | 18 (10%) | 0.503 |
 Alcohol consumption | 287 | 26 (9%) | 8 (8%) | 18 (10%) | 0.675 |
 Drug addiction | 287 | 8 (3%) | 1 (1%) | 7 (4%) | 0.270 |
Long term treatments | |||||
 Benzodiazepine | 287 | 27 (9%) | 12 (12%) | 15 (8%) | 0.253 |
 Antidepressive drug | 287 | 32 (11%) | 11 (11%) | 21 (11%) | 0.988 |
 Neuroleptic | 287 | 18 (6%) | 8 (8%) | 10 (5%) | 0.359 |
Between ICU admission and inclusion | |||||
 SAPS 2 score | 281 | 32 [18–47] | 36 [22–48] | 32 [15–47] | 0.125 |
 Medical admission | 287 | 262 (91%) | 87 (88%) | 175 (93%) | 0.137 |
 Infection | 287 | 174 (61%) | 67 (68%) | 107 (57%) | 0.076 |
 Septic shock | 287 | 62 (22%) | 24 (24%) | 38 (20%) | 0.430 |
 Orotracheal intubation | 287 | 73 (25%) | 23 (23%) | 50 (27%) | 0.534 |
 Tracheostomy | 287 | 11 (4%) | 4 (4%) | 7 (4%) | > 0.99 |
 ARDS | 287 | 29 (10%) | 13 (13%) | 16 (9%) | 0.217 |
24Â h preceding inclusion | |||||
 Maximal SAP (mmHg) | 287 | 143 [129–157] | 140 [130–156] | 145 [129–158] | 0.283 |
 Minimal SAP (mmHg) | 287 | 81 [72–90] | 80 [73–89] | 81 [72–90] | 0.810 |
 Maximal RASS score | 287 | 0 [0–0] | 0 [0–0] | 0 [0–0] | 0.980 |
 Minimal RASS score | 287 | 0 [0–0] | 0 [0–0] | 0 [0–0] | 0.426 |
 Maximal temperature (°C) | 287 | 37 [37–38] | 37 [37–38] | 37 [37–38] | 0.999 |
 Maximal heart rate (bpm) | 287 | 99 [88–114] | 99 [84–109] | 99 [89–116] | 0.202 |
 Minimal heart rate (bpm) | 287 | 80 [69–91] | 75 [64–87] | 82 [71–93] | 0.004 |
 Shock | 287 | 16 (6%) | 7 (7%) | 9 (5%) | 0.423 |
 Noradrenaline infusiona | 287 | 12 (4%) | 4 (4%) | 8 (4%) | > 0.99 |
 Dobutaminea | 287 | 5 (2%) | 4 (4%) | 1 (1%) | 0.050 |
 Antihypertensive drug | 287 | 37 (13%) | 11 (11%) | 26 (14%) | 0.514 |
 Continuous sedation or analgesia | 287 | 16 (6%) | 2 (2%) | 14 (7%) | 0.057 |
 Propofol | 287 | 5 (2%) | 0 (0%) | 5 (3%) | 0.168 |
 Fentanyl | 287 | 2 (1%) | 0 (0%) | 2 (1%) | 0.547 |
 Sufentanyl | 287 | 12 (4%) | 2 (2%) | 10 (5%) | 0.229 |
 Morphine | 287 | 73 (25%) | 22 (22%) | 51 (27%) | 0.364 |
 Morphine cumulative dose (mg) | 33 | 57 [6–221] | 35 [5–113] | 120 [6–324] | 0.240 |
 Neuroleptic | 287 | 2 (1%) | 0 (0%) | 2 (1%) | 0.547 |