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Table 3 Echocardiography, biomarkers and clinical outcome in all patients and stratified by the presence of RV systolic function

From: Incidence of acute myocardial injury and its association with left and right ventricular systolic dysfunction in critically ill COVID-19 patients

  All patients RV systolic function P value
n = 74 Normal
n = 45
Abnormal
n = 13
Echocardiography
Left ventricle
LVEF, % 62 (53 to 67.5) 63 (57 to 70) 54 (50 to 63) 0.018
LVEF <50% 8 (13.6%) 4 (10.3%) 3 (25%) 0.334
LV s’, cm/sec 6 (5 to 7) 6 (4.9 to 6.93) 5 (4.77 to 7.41) 0.813
MAPSE, mm 10.75 (9 to 12.75) 11.25 (9.17 to 13.25) 8.88 (6 to 10.38) 0.004
GLS −17 (−21 to −15) −20 (−22 to −16) −15 (−17 to −10) 0.022
VTI, cm 18.7 (15.4 to 21.9) 20.2 (15.7 to 23) 16 (12.3 to 17.9) 0.011
Right ventricle
TAPSE, mm 18 (16 to 22) 20 (18 to 23) 15 (13 to 16) <0.001
FAC, % 46 (39 to 53) 45 (41 to 54) 47 (34 to 48) 0.267
RVEDA:LVEDA 0.53 (0.46 to 0.57) 0.52 (0.46 to 0.57) 0.56 (0.53 to 0.64) 0.050
RV FWS −23 (−27 to −21) −25 (−30 to −22) −18 (−23 to −13) <0.001
RV TV s’, cm/sec 9.8 (8 to 12) 10 (8 to 12.3) 9 (6 to 9.4) 0.018
hsTnT max, ng/l 53 (21 to 127) 47 (16 to 117) 85 (52 to 239) 0.026
AMInj 60 (82%) 34 (75.6%) 13 (100%) 0.055
Vasopressor days 9.5 (5 to 21.25) 9 (4 to 19) 17 (6 to 24) 0.201
VIS, μg/kg/min 4.34 (1.94 to 7.31) 3.78 (1.31 to 6.94) 4.36 (1.05 to 7.6) 0.929
Proportion requiring IMV 69 (93%) 34 (90%) 14 (93%) 1
IMV days 14.5 (6.8 to 25.5) 14 (6 to 24) 20 (12 to 28) 0.204
SOFA max 10 (7.5 to 12) 9 (7 to 11.5) 9 (8 to 12) 0.503
ICU LOS 17 (8 to 27.5) 18 (8 to 28) 21 (15 to 27) 0.526
ICU mortality 14 (19%) 9 (20%) 1 (7.7%) 1
30-day mortality 13 (18%) 7 (15.6%) 2 (15.4%) 1
  1. P values refer to normal vs. abnormal systolic function
  2. LVEF left ventricular ejection fraction, MV s’ mitral valve tissue colour doppler systolic velocity (average of septal and lateral measurements), MAPSE mitral annular plane systolic excursion, GLS global longitudinal strain, VTI velocity time integral measured at the left ventricular outflow tract, TAPSE tricuspid annular plane systolic excursion, FAC fractional area change, EDA end diastolic area, FWS free wall strain, TV s’ tricuspid valve tissue colour doppler systolic velocity (free wall), hsTnT high sensitivity Troponin T, VIS vasopressor–inotrope score, IMV invasive mechanical ventilation. P values refer to normal vs. abnormal RV systolic function