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Table 2 Baseline characteristics

From: Fluid accumulation and major adverse kidney events in sepsis: a multicenter observational study

Characteristic

All

(n = 1834)

No MAKE30

(n = 1315)

MAKE30

(n = 519)

p value

Age, years

67 (56–75)

66 (55–74)

70 (60–77)

 < 0.001

Male sex

1021 (55.7%)

740 (56.3%)

281 (54.1%)

0.41

Body weight on ICU admission, kga

78 (66–90)

78 (67–91)

75 (64–88)

0.005

Baseline creatinine, µmol/l

123 (81–189)

119 (80–181)

132 (84–214)

0.001

Baseline creatinine approach

0.51

 Obtained from first creatinine level in ICU

1814 (98.9%)

1303 (99.1%)

511 (98.5%)

 

 Obtained from pre-admission creatinine level

5 (0.3%)

3 (0.2%)

2 (0.4%)

 

 Obtained from estimated creatinine level

15 (0.8%)

9 (0.7%)

6 (1.2%)

 

 Chronic liver disease

152 (8.3%)

84 (6.4%)

68 (13.1%)

 < 0.001

 Chronic cardiac disease

307 (16.7%)

203 (15.4%)

104 (20.0%)

0.017

 Chronic respiratory disease

205 (11.2%)

138 (10.5%)

67 (12.9%)

0.14

 Immune deficiency

596 (32.5%)

382 (29.0%)

214 (41.2%)

 < 0.001

Location before ICU admission

 < 0.001

 Other ICU

83 (4.5%)

67 (5.1%)

16 (3.1%)

 

 Emergency department

511 (27.9%)

370 (28.1%)

141 (27.2%)

 

 Recovery

85 (4.6%)

77 (5.9%)

8 (1.5%)

 

 Operating room

202 (11.0%)

151 (11.5%)

51 (9.8%)

 

 High dependency unit

82 (4.5%)

50 (3.8%)

32 (6.2%)32 (6.2%)

 

 Ward

871 (47.5%)

600 (45.6%)

271 (52.2%)

 

Hospital

0.039

 A

552 (30.1%)

409 (31.1%)

143 (27.6%)

 

 B

511 (27.9%)

345 (26.2%)

166 (32.0%)

 

 C

770 (42.0%)

561 (42.7%)

209 (40.3%)

 
  1. Data are n (%) or median (IQR)
  2. MAKE30 major adverse kidney events within 30 days; ICU intensive care unit
  3. aData available for 1289 (98%) patients in the No MAKE30 group and 509 (98%) patients in the MAKE30 group