Skip to main content

Table 1 Patient characteristics according to the occurrence of severe acute kidney injury

From: Impact of early mean arterial pressure level on severe acute kidney injury occurrence after out-of-hospital cardiac arrest

Variables

All patients (n = 568)

Severe AKI

p value

No (n = 294)

Yes (n = 274)

Male, n (%)

404 (71)

219 (74)

185 (67)

0.04

Age, years

59 (49–71)

56 (47–69)

62 (50–72)

< 0.01

BMI, kg/m2

25 (23–28)

25 (22–27)

26 (23–29)

0.16

Hypertension, n (%)

219 (39)

108 (37)

111 (40)

0.89

Diabetes, n (%)

89 (16)

42 (14)

47 (17)

0.62

Witnessed CA, n (%)

491 (86)

262 (89)

229 (84)

0.05

Bystander CPR, n (%)

309 (54)

169 (57)

140 (51)

0.05

VF/VT, n (%)

324 (57)

188 (64)

136 (50)

< 0.01

Epinephrine use during CPR, mg

2.8 ± 3.6

2.2 ± 3.2

3.5 ± 3.8

< 0.01

Time from collapse to CPR, min

4.9 ± 5.5

4.2 ± 4.4

5.8 ± 6.4

< 0.01

Time from CPR to ROSC, min

17.8 ± 11.9

15.2 ± 10.0

20.6 ± 13.1

< 0.01

Iodinated contrast, n (%)

421 (74)

219 (74)

202 (74)

0.90

Coronary angiogram, n (%)

408 (72)

213 (72)

195 (71)

0.28

Admission creatinine level, μmol/L

109 ± 53

94 ± 37

125 ± 63

< 0.01

Admission lactate level, mmol/L

5.0 ± 3.6

3.9 ± 3.8

6.3 ± 4.0

< 0.01

Diuresis within the first 24 h, mL/kg/h

0.9 ± 0.8

1.7 ± 0.6

0.5 ± 0.6

< 0.01

Patients under norepinephrine, n (%)

 At 6 h

175 (31)

76 (26)

99 (36)

< 0.01

 At 12 h

144 (25)

67 (23)

77 (28)

0.16

Norepinephrine dosage, μg/kg/min

 Within first 6 h

0.12 ± 0.36

0.07 ± 0.21

0.18 ± 0.47

< 0.01

 Within first 12 h

0.11 ± 0.32

0.07 ± 0.23

0.15 ± 0.39

< 0.01

Day-30 mortality, n (%)

328 (58)

135 (46)

193 (70)

< 0.01

  1. Data are expressed as mean ± standard deviation, median [interquartile] or number (%)
  2. AKI acute kidney injury, BMI body mass index, CA cardiac arrest, CPR cardiopulmonary resuscitation, VF ventricular fibrillation, VT ventricular tachycardia, ROSC return of spontaneous circulation