Study population | Favourable outcome | Poor outcome | ||
---|---|---|---|---|
N = 80* | N = 50* | N = 30* | p value# | |
General characteristics | ||||
Age, year | 60 [52–71] | 59 [50–67] | 68.5 [55–76] | 0.03 |
Women, n (%) | 23 (28.8%) | 16 (32%) | 7 (23.3%) | |
BMI, kg/m2 | 25.6 [21–30] | 24.2 [21–27] | 28.2 [24–32] | < 0.01 |
Comorbidities | ||||
Pulmonary comorbidities | ||||
Obstructive disease, n. (%) | 18 (22.5%) | 10 (20%) | 8 (26.7%) | 0.58 |
Restrictive disease, n. (%) | 1 (1.3%) | 1 (2%) | 0 (0%) | 1 |
OAS, n. (%) | 9 (11.3%) | 5 (10%) | 4 (13.3%) | 0.72 |
Other pulmonary disease, n. (%) | 2 (2.5%) | 2 (4%) | 0 (0%) | 0.53 |
Home O2-therapy, n. (%) | 2 (2.5%) | 2 (4%) | 0 (0%) | 0.53 |
Home NIV-therapy, n. (%) | 3 (3.8%) | 2 (4%) | 1 (3.3%) | 1 |
Cardiac comorbidities | ||||
Coronary artery disease, n. (%) | 6 (7.5%) | 5 (10%) | 1 (3.3%) | 0.40 |
Heart failure, n. (%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 |
Other comorbidities | ||||
Chronic kidney disease, n. (%) | 4 (5%) | 1 (2%) | 3 (10%) | 0.15 |
Active neoplasia, n. (%) | 22 (27.5%) | 15 (30%) | 7 (23.3%) | 0.61 |
Central neurological disease, n. (%) | 1 (1.3%) | 1 (2%) | 0 (0%) | 1 |
Clinical Frailty Score | 3 [2–5] | 3 [2–5] | 4 [2–5] | 0.83 |
NRS score at admission | 6 [3–6] | 6 [3–6] | 5.5 [4–6] | 0.37 |
Admission data | ||||
Reason for ICU admission | 0.31 | |||
Cardiac arrest | 5 (6.3%) | 3 (6%) | 2 (6.7%) | |
Oliguria/anuria/CRRT need | 2 (2.5%) | 1 (2%) | 1 (3.3%) | |
Respiratory distress | 20 (25%) | 15 (30%) | 5 (16.7%) | |
Shock | 9 (11.3%) | 5 (10%) | 4 (13.3%) | |
Post-operative (planned) | 6 (7.5%) | 6 (12%) | 0 (0%) | |
Post-operative (emergency surgery) | 11 (13.8%) | 4 (8%) | 7 (23.3%) | |
Polytrauma | 6 (7.5%) | 4 (8%) | 2 (6. 7%) | |
Other hospital transfer | 5 (6.3%) | 3 (6%) | 2 (6. 7%) | |
Altered level of consciousness | 16 (20%) | 9 (18%) | 7 (23.3%) | |
Type of ICU admission | 1 | |||
Medical, n. (%) | 28 (35%) | 18 (36%) | 10 (33.3%) | |
Surgical, n. (%) | 52 (65%) | 32 (64%) | 20 (66. 7%) | |
SAPS II at admission | 46.5 [39–62] | 44.5 [36–64] | 51.0 [43–61] | 0.33 |
SOFA Score at admission | 9.0 [7–11] | 8.0 [7–11] | 9.0 [7–11] | 0.89 |
Neurological reason for intubation | 23 (28.8%) | 11 (22%) | 12 (40%) | 0.13 |