Kinetics of capillary refill time after fluid challenge

Annals of Intensive Care

Table 2 Global hemodynamic and tissue parameters at baseline and 30 min after fluid infusion parameters

Parameters	Baseline	30 min	P value
Heart rate, bpm	106 [95–125]	103 [90–124]	0.01
Blood pressure
Systolic, mmHg	100 [94–123]	109 [95–131]	0.05
Diastolic, mmHg	59 [55–69]	62 [56–67]	0.51
Mean, mmHg	71 [68–83]	78 [69–86]	0.11
Norepinephrine, μg/kg/min	0.10 [0–0.40]	0.10 [0–0.40]	1
Cardiac index, L/min/m2	2.8 [2.2–3.7]	3.4 [2.3–4.3]	0.12
Capillary refill time	3.8 [2.6–4.1]	2.5 [1.5–3.4]	< 0.0001
Mottling score	2 [1–3]	2 [0–3]	0.13

Values are given as median [25th–75th percentiles]. Comparisons were done using paired non-parametric test. Global hemodynamic and tissue perfusion parameters baseline and 30 min after fluid infusion in responders (N = 23)
Bold values indicate statistically differences between groups