p-ARDS n = 31 | ep-ARDS n = 8 | p value | |
---|---|---|---|
Age (years) | 1.7 (0.3–5.9) | 5.80 (0.7–8.8) | 0.32 |
Weight (kg) | 11.4 (5.5–22) | 21 (8.2–30) | 0.31 |
PIM2 (%) | 3.8 (1.5–10.4) | 5.9 (4–13.1) | 0.28 |
Duration of PICU stay (days) | 14 (10–26) | 29 (18–38) | 0.038 |
Duration of invasive mechanical ventilation (days) | 10 (7–16) | 14 (10–31.5) | 0.08 |
Duration of non-invasive mechanical ventilation (days) | 2 (0–4) | 0 (0–1.5) | 0.12 |
Duration of O2 dependence (days) | 11 (5–21) | 15.5 (8–28.5) | 0.42 |
Length of hospital stay (days) | 19.5 (11.5–38.5) | 33.5 (27–42) | 0.054 |
Max VTE (ml/kg) | 7.8 (6.4–11.1) | 7.8 (6.1–10.6) | 0.94 |
Max PEEP (cmH2O) | 10 (8–12) | 13 (11–14.9) | 0.046 |
Max PImax (cmH2O) | 44 (34–45) | 46 (37–58 | 0.41 |
Max Pplat (cmH2O) | 28 (24–38) | 32 (26–45) | 0.21 |
Duration of ventilation with inverse I/E ratio (days) | 0 (0–0) | 0 (0–1) | 0.40 |
Max FiO2* | 100 (100–100) | 100 (92.5–100) | 0.091 |
Worse PaO2/FiO2 ratio* | 58 (49–69) | 46.5 (40–71.3) | 0.20 |
Days with FiO2 > 60% | 5 (3–10) | 5.5 (3–9.5) | 0.73 |
Max resp PELOD | 10 (10–10) | 10 (1–10) | 0.10 |
Max total PELOD | 21 (20–22) | 20 (12–21) | 0.36 |
Max Lung Injury Score | 3.3 (3.3–3.8) | 3.50 (3.0–3.8) | 0.81 |
Max Oxygenation Index | 31.4 (23.7–40) | 32.6 (22.6–57.1) | 0.66 |
Max Ventilation Index | 630 (480–760) | 897 (644–1088) | 0.14 |
General corticosteroid administration | 25 (80.7%) | 7 (87.5%) | 1 |
Hydrocortisone total dose/body weight (mg/kg) | 67.6 (27.6–96) | 38.7 (14.8 to 117.4) | 0.78 |
Hydrocortisone bolus | 7 (29.2%) | 3 (42.8%) | 0.65 |
HFO | 15 (48.4%) | 1 (12.5%) | 0.11 |
NO | 14 (46.7%) | 3 (37.5%) | 0.71 |
ECLS | 6 (20.0%) | 0 | 0.31 |
Neuromuscular blocking agents | 24 (77.4%) | 5 (62.5%) | 0.40 |
Surfactant administration | 1 (3.2%) | 0 | NA |