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Table 2 Characteristics of the 39 children during their PICU stay by type of ARDS

From: Whole pulmonary assessment 1 year after paediatric acute respiratory distress syndrome: prospective multicentre study

  p-ARDS n = 31 ep-ARDS n = 8 p value
Age (years) 1.7 (0.3–5.9) 5.80 (0.7–8.8) 0.32
Weight (kg) 11.4 (5.5–22) 21 (8.2–30) 0.31
PIM2 (%) 3.8 (1.5–10.4) 5.9 (4–13.1) 0.28
Duration of PICU stay (days) 14 (10–26) 29 (18–38) 0.038
Duration of invasive mechanical ventilation (days) 10 (7–16) 14 (10–31.5) 0.08
Duration of non-invasive mechanical ventilation (days) 2 (0–4) 0 (0–1.5) 0.12
Duration of O2 dependence (days) 11 (5–21) 15.5 (8–28.5) 0.42
Length of hospital stay (days) 19.5 (11.5–38.5) 33.5 (27–42) 0.054
Max VTE (ml/kg) 7.8 (6.4–11.1) 7.8 (6.1–10.6) 0.94
Max PEEP (cmH2O) 10 (8–12) 13 (11–14.9) 0.046
Max PImax (cmH2O) 44 (34–45) 46 (37–58 0.41
Max Pplat (cmH2O) 28 (24–38) 32 (26–45) 0.21
Duration of ventilation with inverse I/E ratio (days) 0 (0–0) 0 (0–1) 0.40
Max FiO2* 100 (100–100) 100 (92.5–100) 0.091
Worse PaO2/FiO2 ratio* 58 (49–69) 46.5 (40–71.3) 0.20
Days with FiO2 > 60% 5 (3–10) 5.5 (3–9.5) 0.73
Max resp PELOD 10 (10–10) 10 (1–10) 0.10
Max total PELOD 21 (20–22) 20 (12–21) 0.36
Max Lung Injury Score 3.3 (3.3–3.8) 3.50 (3.0–3.8) 0.81
Max Oxygenation Index 31.4 (23.7–40) 32.6 (22.6–57.1) 0.66
Max Ventilation Index 630 (480–760) 897 (644–1088) 0.14
General corticosteroid administration 25 (80.7%) 7 (87.5%) 1
Hydrocortisone total dose/body weight (mg/kg) 67.6 (27.6–96) 38.7 (14.8 to 117.4) 0.78
Hydrocortisone bolus 7 (29.2%) 3 (42.8%) 0.65
HFO 15 (48.4%) 1 (12.5%) 0.11
NO 14 (46.7%) 3 (37.5%) 0.71
ECLS 6 (20.0%) 0 0.31
Neuromuscular blocking agents 24 (77.4%) 5 (62.5%) 0.40
Surfactant administration 1 (3.2%) 0 NA
  1. Crs respiratory system compliance, ECLS extracorporeal life support, ep-ARDS extra-pulmonary, HFO high-frequency oscillation, I/E ratio inspiratory/expiratory ratio, p-ARDS pulmonary ARDS, PEEP positive end-expiratory pressure, PELOD score Paediatric Logistic Organ Dysfunction Score, PICU paediatric intensive care unit, PIMax maximal inspiratory pressure, PIM2 paediatric index of mortality score 2, Pplat plateau pressure, NA not applicable, NO inhaled nitric oxide, VTE expiratory tidal volume
  2. Results are medians (interquartile ranges) for quantitative variables, and frequencies and percentages for categorical variables. *For NO: missing data in 1 child. *Worst PaO2/FiO2 ratio and max FiO2 during the PICU stay