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Table 5 Summary of abnormalities in PFT (all ages) in 35 children by type of ARDS

From: Whole pulmonary assessment 1 year after paediatric acute respiratory distress syndrome: prospective multicentre study

Abnormality n p-ARDS n = 27
23 children (85%)
ep-ARDS n = 8
7 children (88%)
Hyperinflation and/or obstructive pattern 12/35 9 3
 Hyperinflation [functional residual capacity (FRC), total lung capacity (TLC)] 7/30 4 3
 Obstruction [resistance by interruption technique (Rint), total lung resistance by oesophageal-balloon technique (RL)] 11/19 9 2
 Associated to a decrease in lung dynamic compliance (CLdyn /FRC) 7/9 7 0
Restrictive abnormalities 6/12 4 2
 True restrictive ventilatory defect (TLC) in 4/11 children   3 1
 and/or decrease in FVC and FEV1 together with a FEV1/FVC ratio ≥ LLN suggestive of a restrictive ventilatory defect in 4/12 children   2 2
Decrease in carbon monoxide transfer factor (TLCO) 3/8 2 1
Hypoxemia 2/14 1 1
Decrease in inspiratory muscle strength (SNIP) 2/13 2 0
Decrease in 6-min-walking distance 11/15 9 2
Desaturation at the end of a 6-min-walk test 1/16 1 0
  1. FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, ep-ARDS extra-pulmonary ARDS. p-ARDS pulmonary ARDS, PFT pulmonary function tests, SNIP sniff nasal inspiratory pressure