Table 6 Correlation matrix (spearman correlation) of physiologic parameters/ventilator settings, CT scan, and PFTs

CT-scan abnormalities

− 0.2254

0.23702

0.42332

0.27985

− 0.18168

0.14739

0.1027

0.1798

0.2648

0.0278

0.1574

0.2889

0.3772

0.6252

37

24

27

27

36

38

25

Ground glass opacities

− 0.28551

0.29183

0.41003

0.2727

− 0.08419

0.22173

0.1993

0.0867

0.1664

0.0337

0.1688

0.6254

0.1809

0.3395

37

24

27

27

36

38

25

Parenchymal consolidations

− 0.27678

− 0.2602

0.3842

0.15842

− 0.05876

− 0.10985

− 0.05518

0.0972

0.2195

0.0479

0.43

0.7335

0.5115

0.7933

37

24

27

27

36

38

25

Septal reticulation

0.03512

0.06435

− 0.09486

0.04296

− 0.10981

− 0.15434

− 0.2817

0.8365

0.7652

0.6379

0.8315

0.5238

0.3549

0.1725

37

24

27

27

36

38

25

Honey combing

− 0.00393

− 0.12242

0.05054

0.06321

− 0.16435

− 0.18822

− 0.08341

0.9816

0.5688

0.8023

0.7541

0.3382

0.2578

0.6918

37

24

27

27

36

38

25

Centrilobular cysts

− 0.26548

− 0.2034

− 0.06868

0.1123

0.2341

0.682

37

24

27

27

36

38

25

Paraseptal cysts

− 0.17358

− 0.2034

− 0.09846

0.3042

0.2341

0.5564

37

24

27

27

36

38

25

Fissure thickening and distortions

− 0.08342

− 0.11809

0.02315

− 0.22449

− 0.30531

− 0.02586

0

0.6235

0.5826

0.9087

0.2603

0.0702

0.8775

1

37

24

27

27

36

38

25

Bronchiectasis

− 0.05191

0.06128

0.32053

0.33418

0.11382

0.01895

0.09159

0.7603

0.7761

0.1031

0.0884

0.5086

0.9101

0.6633

37

24

27

27

36

38

25

Mosaic perfusion

− 0.17837

0.17357

0.14341

0.06746

− 0.29036

0.31527

0.31858

0.2909

0.4173

0.4754

0.7381

0.0858

0.0539

0.1206

37

24

27

27

36

38

25

FRC, % predicted

− 0.29732

0.27218

0.39217

0.38531

0.40472

0.05856

0.48912

0.1106

0.2457

0.0475

0.0472

0.0265

0.7586

0.0244

30

20

26

27

30

30

21

R_int, % predicted

− 0.37828

0.83333

− 0.02462

0.1549

0.36364

0.21751

0.18333

0.2253

0.0053

0.9462

0.6493

0.2453

0.4971

0.6368

12

9

10

11

12

12

9

R_L, % of predicted

− 0.05858

0.64672

0.45238

− 0.08513

− 0.41917

0.881

0.0831

5

5

0.2604

0.8276

0.3013

9

8

8

9

8

C_Ldyn, % predicted

0.56067

− 0.7545

0.38095

− 0.70654

0.38324

0.1163

0.0305

5

5

0.3518

0.0333

0.3487

9

8

8

9

8

FVC, z-score

− 0.34266

− 0.53522

− 0.47101

0.37762

0.08669

6

0.2756

5

0.0729

0.1222

0.2262

0.7888

12

12

12

12

12

FEV₁, z-score

− 0.25874

− 0.26409

− 0.25659

0.3007

0.0903

6

0.4168

5

0.4069

0.4208

0.3423

0.7802

12

12

12

12

12

FEV₁/FVC ratio, z-score

0.09091

0.52466

0.30932

− 0.24476

0.1517

0.7787

5

0.0799

0.3279

0.4433

0.6379

12

12

12

12

12

6

SpO₂ (end of 6MWT), %

− 0.41912

7

− 0.35946

− 0.13085

− 0.04531

0.28603

7

0.1199

0.2277

0.67

0.8726

0.3014

15

13

13

15

15

T_LCO, z-score

0.2381

− 0.23953

− 0.27545

0

− 0.31709

0.5702

0.5678

0.5091

1

0.4441

4

8

3

8

8

8

8