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Annals of Intensive Care

Table 1 Characteristics of patient population, days of hospital stay, mortality

From: A burden of fluid, sodium, and chloride due to intravenous fluid therapy in patients with respiratory support: a post-hoc analysis of a multicenter cohort study

 

All patients

Without hypoxemia (P/F ratio > 300)

Mild hypoxemia (150 < P/F ratio ≤ 300)

Severe hypoxemia (P/F ratio ≤ 150)

P value

N = 588

N = 167

N = 297

N = 124

Age, mean (SD), y

67.5 (15.7)

62.2 (19.4)

69.4 (13.6)

69.9 (12.8)

 < 0.001

Male, n (%)

380 (64.6)

96 (57.5)

193 (65.0)

91 (73.4)

0.019

Body mass index, mean (SD), kg/m2

23.1 (4.3)

21.9 (3.5)

22.9 (21.1–25.8)

24.2 (4.4)

 < 0.001

Patient admission category

 < 0.001

 Non-scheduled surgery, n (%)

138 (23.4)

43 (25.8)

73 (24.6)

22 (17.7)

 

 Scheduled surgery, n (%)

150 (25.5)

60 (35.9)

73 (24.6)

17 (13.7)

 

 Medical emergency, n (%)

300 (51.0)

64 (38.3)

151 (50.8)

85 (68.6)

 

 APACHE II score, median (IQR)

19 (13.5–24)

16 (11–22)

18 (14–24)

21 (17–27)

0.001

 SOFA score, median (IQR)

7 (5–10)

5 (3–7)

8 (6–10)

8.5 (6.5–11)

0.001

 Charlson comorbidity index, median (IQR)

4 (2–6)

3 (1–5)

5 (3–6)

4 (3–6)

 < 0.001

Sepsis category

0.006

 Sepsis, n (%)

48 (8.2)

8 (4.8)

26 (8.8)

14 (11.3)

 

 Septic shock, n (%)

74 (12.6)

11 (6.6)

43 (14.5)

20 (16.1)

 

Acute kidney injury

 < 0.001

 Stage 1, n (%)

49 (8.3)

8 (4.8)

22 (7.4)

19 (15.3)

 

 Stage 2, n (%)

31 (5.3)

4 (2.4)

16 (5.4)

11 (8.9)

 

 Stage 3, n (%)

58 (9.9)

12 (7.2)

31 (10.4)

15 (12.1)

 

Respiratory supportc

0.004

 Noninvasive ventilation, n (%)

80 (13.6)

12 (7.2)

43 (14.5)

25 (20.2)

 

 Invasive ventilation, n (%)

508 (86.4)

155 (92.8)

254 (85.5)

99 (79.8)

 

 P/F ratioc, median (IQR)

226.5 (162–317.5)

368 (335–418)

217 (187–256)

114.5 (90–132)

 < 0.001

 Length of ICU Staya, median (IQR), h

108.1 (58.9–191.0)

68.7 (43.7–131.4)

110.3 (65.5–211.4)

141.8 (97.2–249.6)

0.001

ICU mortality, n (%)

44 (7.5)

9 (5.4)

18 (6.1)

17 (13.7)

0.019

 Length of hospitalizationb, median (IQR), d

31 (19–56)

26.5 (15–52)

32 (19–57)

35 (23–58)

0.032

 Hospital mortality, n (%)

102 (17.4)

17 (10.2)

50 (16.8)

35 (28.2)

0.003

  1. aExcluded 40 patients who were died during ICU stay
  2. bExcluded 102 patients who were died during hospital stay
  3. cAt ICU admission
  4. APACHE acute physiology and chronic health evaluation, ICU intensive care unit, IQR interquartile range, P/F ratio ratio of arterial oxygen partial pressure to fractional inspired oxygen, SD standard deviation, SOFA sequential organ failure assessment
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