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Annals of Intensive Care

Table 2 Association between frailty, delirium and in-hospital mortality and length of stay

From: Association between frailty, delirium, and mortality in older critically ill patients: a binational registry study

 

Risk of in-hospital mortality

P-value

Log transformed length of hospital stay

P-value

Adjusted odds ratio (95% CI)

Mean difference (95% CI)

Frailty

    

 No

Ref

 

Ref

 

 Yes

2.15 (2.05–2.25)

 < 0.001

0.24 (0.23–0.25)

 < 0.001

Episode of delirium#

    

 No

Ref

 

Ref

 

 Yes

1.32 (1.23–1.43)

 < 0.001

0.52 (0.50–0.54)

 < 0.001

Frailty predicting delirium

    

Frailty

    

 No

Ref

   

 Yes

1.86 (1.77–1.95)

 < 0.001

  

Interaction between frailty and delirium

    

 Not frail- without delirium

Ref

 

Ref

 

 Not frail—with delirium

1.37 (1.23–1.52)

 < 0.001

0.62 (0.60–0.65)

 < 0.001

 Frail—no delirium

2.14 (2.04–2.24)

 < 0.001

0.24 (0.23–0.25)

 < 0.001

 Frail with delirium

2.77 (2.51–3.05)

 < 0.001

0.62 (0.59–0.65)

 < 0.001

  1. Adjusted for Australian and New Zealand Risk of Death (ANZROD). ANZROD is derived from patient and clinical characteristics, including the Acute Physiology and Chronic Health Evaluation (APACHE) III, ICU admission source, admission diagnoses, Acute Physiology score (APS), APACHE III chronic health score, treatment limitation, and ventilation status
  2. #Adjusted for ANZROD and frailty
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