Table 1 Patient characteristics, respiratory mechanics, and recruitability assessment
Parameter | n = 33 |
|---|---|
Age, years | 57 [50–64] |
Sex, M, n (%) | 21 (63.6) |
Height, cm | 168.0 [156.0–172.0] |
Body weight, kg | 74.3 [62.0–85.0] |
Body mass index, kg/m2 | 27.5 [23.8–29.0] |
Pre-existing conditions, n (%) | |
COPD | 12 (36.4) |
Hypertension | 12 (36.4) |
Diabetes | 26 (78.8) |
Receiving high-flow nasal cannula before invasive mechanical ventilation, n (%) | 12 (36.4) |
Receiving prone position after invasive mechanical ventilation, n (%) | 32 (97.0) |
Interval between onset and admission | 10 [6–11] |
Severity of ARDS at admission, n (%) | |
Mild | 5 (15.2) |
Moderate | 18 (54.6) |
Severe | 8 (24.2) |
KL-6 at admission | 571 [318–841] |
APACHE II at admission | 13 [8–15] |
Interval between start of mechanical ventilation and recruitability assessment, days | 0 [0–1] |
PaO2/FiO2 at recruitability assessment, mmHg | 116.0 [90.0–183.0] |
SOFA score at recruitability assessment | 3 [2–7] |
Respiratory data at recruitability assessment | |
TV, mL/kg (PBW) | 6.2 [5.8–7.4] |
PEEP, cm H2O | 15 [14, 15] |
Pplat, cm H2O | 25 [23–29] |
Crs, mL/cm H2O | 36.6 [30.1–44.4] |
Recruitability assessment | |
Airway opening pressure > 5 cm H2O, n (%) | 7 (21.2) |
Higher PEEP for R/I ratio, cm H2O | 15 [15–15] |
Set tidal volume for R/I ratio, mL | 400 [400–400] |
VT exhaled at higher PEEP for R/I ratio, mL | 390 [380–400] |
Lower PEEP for R/I ratio, cm H2O | 5 [5–5] |
VT exhaled from higher to lower PEEP, mL | 1145 [959–1280] |
Plateau pressure at lower PEEP for R/I ratio, cm H2O | 15 [14–18] |
∆Vrec, mL | 334.3 [260.0–451.4] |
R/I ratio | 0.90 [0.70–1.15] |
Distance at 20 cm H2O, mL | 810 [645–970] |
Maximal distance, mL | 845 [670–995] |
Airway pressure at maximal distance, cm H2O | 19.5 [17.9–20.4] |
Maximal volume (Vmax), mL | 2065 [1710–2625] |
Normalized distance at 20 cm H2O, % | 39.9 [35.8–42.6] |
Normalized maximal distance, % | 41.0 [37.1–44.1] |