Total (n = 417) | Group A (n = 191) | Group B (n = 128) | Group C (n = 98) | p-value | |
---|---|---|---|---|---|
Age, years, median (IQR) | 62 (52–68) | 61 (52–68) | 61 (47–67) | 63 (54–69) | 0.188 |
Sex, n (%) | |||||
Male | 301 (72.2) | 135 (70.7) | 95 (74.2) | 71 (72.4) | 0.796 |
Female | 116 (27.8) | 56 (29.3) | 33 (25.8) | 27 (27.6) | 0.796 |
Body mass index (kg/m2), median (IQR) | 30 (27–34) | 29 (26–33) | 30 (26–34) | 31 (27–35) | 0.098 |
Comorbidities, n (%) | |||||
Hypertension | 232 (55.6) | 108 (56.5) | 70 (54.7) | 54 (55.1) | 0.951 |
Type 2 diabetes mellitus | 166 (39.8) | 85 (44.5) | 43 (33.6) | 38 (38.8) | 0.148 |
Coronary heart disease | 17 (4.1) | 6 (3.1) | 3 (2.3) | 8 (8.2) | 0.074 |
Chronic liver disease | 10 (2.4) | 5 (2.6) | 4 (3.1) | 1 (1) | 0.652 |
Immunosuppression | 6 (1.4) | 5 (2.6) | – | 1 (1) | 0.144 |
Chronic kidney disease | 20 (4.8) | 13 (6.8) | 3 (2.3) | 4 (4.1) | 0.182 |
Obesity | 147 (35.3) | 61 (31.9) | 47 (36.7) | 39 (39.8) | 0.368 |
Other | 121 (29) | 58 (30.4) | 35 (27.3) | 28 (28.6) | 0.842 |
None | 63 (15.1) | 32 (16.8) | 18 (14.1) | 13 (13.3) | 0.712 |
APACHE II score, median (IQR) | 14 (10–18) | 14 (10–18) | 14 (10–18) | 13 (10–17) | 0.748 |
SOFA score, median (IQR) | 5 (4–7) | 5 (4–8) | 5 (4–7) | 4 (4–6) | 0.246 |
Sepsis, n (%) | 100 (24.3) | 37 (19.7) | 29 (22.8) | 34 (35.1) | 0.017 |
Time between (days), median (IQR) | |||||
Diagnosis to hospital admission | 0 (0–3) | 0 (0–3) | 0 (0–4) | 0 (0–1) | 0.096 |
Hospital to ICU admission | 1 (0–3) | 1 (0–3) | 1 (0–3) | 1 (0–4) | 0.086 |
Diagnosis to invasive ventilation | 3 (1–6) | 3 (0–6) | 3 (1–7) | 3 (1–5) | 0.940 |
Invasive ventilation to prone position | 1 (0–1) | 1 (0–2) | 1 (0–2) | 0 (0–1) | < 0.001 |