Table 1 Characteristics of patients with necrotizing soft tissue infections (n = 170) at intensive care unit admission
N | Total | |
|---|---|---|
N = 170 | ||
Demographic data | ||
Age | 170 | 59 [53–68.8] |
Sex | 170 | |
Male | 122 (71.8) | |
Female | 48 (28.2) | |
NSTI characteristics | ||
Hospital-acquired NSTI | 170 | 38 (22.4) |
Topography | ||
Upper limb | 170 | 24 (14.1) |
Lower limb | 170 | 121 (71.2) |
Abdominal/perineal | 170 | 33 (19.4) |
Multifocal | 170 | 8 (4.7) |
Comorbidities | ||
Immunosuppressiona | 170 | 43 (25.3) |
Cancer | 43 | 14 (32.5) |
Neutropenia | 43 | 5 (11.6) |
HIV infection | 43 | 4 (9.3) |
Long-term corticosteroids | 43 | 26 (60.5) |
PAOD | 170 | 26 (15.3) |
Diabetes | 170 | 94 (55.3) |
Chronic heart failure | 170 | 38 (22.4) |
COPD | 169 | 17 (10.1) |
Cirrhosis | 169 | 15 (8.9) |
Chronic hemodialysis | 170 | 5 (2.9) |
Chronic alcohol intoxication | 170 | 49 (28.8) |
NSAIDs use before hospitalization | 168 | 37 (22.0) |
Obesity | 170 | 60 (35.3) |
Microbiological data | ||
Number of isolated bacteria | 156 | 2 [1–3] |
NSTI categorization | 154 | |
Type II (monomicrobial) | 65 (42.2) | |
Type I (polymicrobial) | 89 (57.8) | |
Positive blood culture | 170 | 50 (29.4) |
Isolation of multi / highly resistant bacteria | 168 | 29 (17.3) |
Severity scores and organ failures | ||
SAPS II | 161 | 46 [30–63] |
SOFA | 161 | 8 [4–12] |
Organ failures within the first 24 h of ICU admission | 163 | 115 (70.6) |
Invasive mechanical ventilation support | 163 | 55 (33.7) |
Vasopressor support | 163 | 113 (69.3) |
Renal replacement therapy | 163 | 35 (21.5) |
Post-surgical ICU admission | 163 | 48 (29.5) |