Annals of Intensive Care

Table 2 Univariable and multivariable subdistribution hazard models for time to catheter removal for absence of further utility in the training cohort (n = 2336)

From: Development and validation of a multivariable model predicting the required catheter dwell time among mechanically ventilated critically ill patients in three randomized trials

Risk factors	Univariable analysis			Multivariable analysis
Risk factors	HR¹	95% CI²	p-value	Adjusted HR¹	95% CI²	p-value
Male	0.87	[0.79–0.97]	0.014
Age			< 0.001*			< 0.001*
< 40 years	1	–	–	1	–	–
40–59 years	0.65	[0.54–0.78]	< 0.001	0.70	[0.58–0.85]	< 0.001
60–69 years	0.54	[0.44–0.66]	< 0.001	0.63	[0.51–0.77]	< 0.001
70–74 years	0.49	[0.39–0.62]	< 0.001	0.58	[0.46–0.74]	< 0.001
75–80 years	0.45	[0.36–0.57]	< 0.001	0.56	[0.44–0.71]	< 0.001
≥ 80 years	0.51	[0.41–0.63]	< 0.001	0.62	[0.50–0.78]	< 0.001
Body temperature ≥ 39 °C	0.94	[0.76–1.17]	0.60
Diabetes	0.78	[0.68–0.90]	< 0.001	–	–	–
Obesity³	0.84	[0.74–0.95]	0.006	0.85	[0.75–0.96]	0.012
Vasopressors use	0.70	[0.63–0.78]	< 0.001	0.78	[0.70–0.87]	< 0.001
Immunosuppression	0.62	[0.51–0.75]	< 0.001	0.64	[0.52–0.77]	< 0.001
Creatinine > 100 µmol/L	0.59	[0.53–0.66]	< 0.001	0.66	[0.59–0.74]	< 0.001

¹HR hazard ratio: values < 1 reflect longer catheter dwell time
²CI confidence interval
³Body mass index ≥ 30 kg/m²
*p-value is for type III effect
Bold values denote statistical significance

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