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Table 3 Sensitivity, specificity, positive and negative predictive values at different time horizons for CVC-IN score ≥ 4 points in the training and testing cohorts

From: Development and validation of a multivariable model predicting the required catheter dwell time among mechanically ventilated critically ill patients in three randomized trials

Time horizon

Training cohort (n = 2,336)

Testing cohort (n = 2,371)

Value (%)

95% CI1

Value (%)

95% CI1

7 days

 Sensitivity

63.9

[60.4–67.4]

57.6

[53.7–61.5]

 Specificity

55.3

[52.8–57.8]

54.1

[51.8–56.4]

 Positive predictive value

74.2a

[71.5–76.9]

76.9

[74.4–79.4]

 Negative predictive value

43.1

[40.3–45.9]

32.5

[29.7–35.3]

14 days

 Sensitivity

61.8

[58.9–64.7]

55.4

[52.4–58.4]

 Specificity

61.3

[58.1–64.5]

57.3

[54.5–60.1]

 Positive predictive value

57.3

[54.2–60.4]

58.7

[55.8–61.6]

 Negative predictive value

65.6

[62.6–68.6]

54.0

[51.0–57.0]

28 days

 Sensitivity

59.9

[57.2–62.6]

55.6

[52.8–58.4]

 Specificity

69.5

[66.3–72.7]

64.4

[61.7–67.1]

 Positive predictive value

42.2

[39.0–45.4]

44.6

[41.5–47.7]

 Negative predictive value

82.4

[80.0–84.8]

73.7

[70.9–76.5]

  1. 1CI confidence interval
  2. aFor example, the probability of needing a central-venous access for at least 7 days when the CVC-IN score is ≥ 4 points is 0.742 in the training cohort