Table 1 Patient characteristics

Age^a

70 (46, 76)

63 (57, 77)

Sex-ratio

6.5

2

Baseline APACHE II^a

19 (14, 20)

15 (9, 19)

Baseline SOFA Score^a

8 (5, 10)

10 (7, 11)

Source of infection, (n (%))

 - Pulmonary

 - Intra-abdominal

 - Blood stream

 - Skin and soft tissue

 - Endocarditis

 - Urinary tract

5 (24%)

5 (24%)

2 (10%)

2 (10%)

1 (5%)

0

3 (14%)

0

2 (10%)

0

0

1 (5%)

Creatinine, (mmol/L)^a

115 (78, 224)

155 (80, 553)

White blood cell, (G/L)^a

15 (10, 20)

15 (12, 15)

Lymphocytes, (G/L) ^a

0.6 (0.4, 1.0)

0.6 (0.3, 0.9)

CD4 T cells, (10³cells/µL)^a

0.326 (0.185, 0.673)

0.637 (0.164, 0.703)

CD8 T cells, (10³cells/µL)^a

0.112 (0.50, 0.216)

0.134 (0.28, 0.170)

mHLA-DR, (mAB/cell)^a

4153 (2490, 8010)

7679 (3938, 13,481)

Neutrophils, (G/L)^a

12 (9, 18)

12 (10, 13)

Monocytes, (G/L)^a

0.5 (0.4, 1.0)

0.8 (0.7, 0.8)

Platelets, (G/L)^a

130 (58, 256)

87 (74, 96)