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Table 2 Microbiological documentation in NSTIs according to neutropenic status

From: Necrotizing soft tissue infections in critically ill neutropenic patients: a French multicentre retrospective cohort study

Isolated bacteria

Non-neutropenic patients

Neutropenic patients

p-value

N = 149

N = 76

Gram-negative bacteria

 Enterobacterales

52 (34.9)

34 (44.7)

0.15

  Escherichia coli

23 (15.4)

19 (25)

0.08

  Enterobacter cloacae

6 (4)

3 (3.9)

 

  Klebsiella pneumoniae

10 (6.7)

4 (5.3)

 

  Proteus mirabilis

11 (7.4)

1 (1.3)

 

  Citrobacter spp

5 (3.4)

2 (2.6)

 

  Klebsiella oxytoca

3 (2)

0 (0)

 

  Morganella morganii

3 (2)

0 (0)

 

  Serratia marcescens

4 (2.7)

1 (1.3)

 

  Unprecised

 

6 (7.9)

 

 Non-fermenting bacteria

26 (17.4)

29 (38.2)

< 0.001

  Pseudomonas aeruginosa

24 (16.1)

24 (31.6)

0.007

  Acinetobacter spp.

4 (2.7)

1 (1.3)

 

  Pseudomonas stutzeri

0 (0)

1 (1.3)

 

  Stenotrophomonas maltophilia

0 (0)

3 (3.9)

 

Gram-positive bacteria

   

 Streptococcus pyogenes

38 (25.5)

0 (0)

< 0.001

 Other streptococcus species

47 (31.5)

8 (10.5)

< 0.001

  Streptococcus agalactiae

10 (6.7)

0 (0)

 

  Streptococcus anginosus

12 (8.1)

0 (0)

 

  Streptococcus constellatus

5 (3.4)

1 (1.3)

 

  Streptococcus oralis

4 (2.7)

0 (0)

 

  Streptococcus dysgalactiae

5 (3.4)

1 (1.3)

 

  Enterococcus faecium

8 (5.4)

3 (3.9)

 

  Enterococcus faecalis

14 (9.4)

2 (2.6)

 

  Enterococcus durans

0 (0)

1 (1.3)

 

 Staphylococcus aureus

38 (25.5)

3 (3.9)

< 0.001

 Staphylococcus coag neg

7 (4.7)

6 (7.9)

 

Anaerobic bacteria

15 (10.1)

6 (7.9)

0.59

Other

11 (7.4)

5 (6.6)

0.82

Undocumented

7 (9.2)