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Table 3 Regression analyses for ICU mortality including all patients

From: The Clinical Frailty Scale for mortality prediction of old acutely admitted intensive care patients: a meta-analysis of individual patient-level data

Complete case analysis—Model including only Frailty (n = 22,044)

  

HR1 (95%CI)

P-value

Frailty

vulnerable (CFS 4)

1.26 (1.11–1.43)

0.00024

 

frail (CFS 5–8)

1.59 (1.53–1.66)

 < 0.0001

Models including all variables available at baseline

Complete Case Analysis—Model including SOFA as severity index (n = 20,767)

  

HRa (95%CI)

P-value

Frailty

vulnerable (CFS 4)

1.07 (1.03–1.1)

0.00054

 

frail (CFS 5–8)

1.26 (1.15–1.38)

 < 0.0001

Severity

SOFA (one point increase)

1.17 (1.1–1.23)

 < 0.0001

Gender

male vs female

0.97 (0.91–1.04)

0.3591

Age

Age (5 years increase)

1.11 (1.09–1.13)

 < 0.0001

Multiple Imputation Analysis—Model including SOFA as severity index

  

HR1 (95%CI)

P-value

Frailty

vulnerable (CFS 4)

1.07 (1.03–1.11)

0.00139

 

frail (CFS 5–8)

1.28 (1.15–1.41)

 < 0.0001

Severity

SOFA (one point increase)

1.17 (1.11–1.23)

 < 0.0001

Gender

male vs female

0.96 (0.9–1.02)

0.15900

Age

Age (5 years increase)

1.11 (1.09–1.13)

 < 0.0001

  1. aReference "fit" defined as CFS score 1–3