Table 2 Studies showing that short-course antibiotic regimens are non-inferior to long-course antibiotic regimens
From: Antibiotic stewardship in the ICU: time to shift into overdrive
Infection site | Short-course regimen (days) | Long-course regimen (days) | References |
|---|---|---|---|
Uncomplicated Gram-negative bloodstream infection | 7 | 14 | [157] |
Acute exacerbation of COPD |  =  < 5 |  >  = 7 | [187] |
Community-acquired pneumonia | 3–5 | 7–10 | |
HAP and VAP | 7–8 | 14–15 | |
Intra-abdominal infections and post-operative peritonitis | 4–8 | 10–15 | |
Severe community-acquired UTI | 5–7 | 10–14 | |
Cellulitis | 5–6 | 10 | |
Neutropenia | 3 days of apyrexia and clinical recovery | 3 days of apyrexia and clinical recovery and neutrophil count > 0,5 × 109 cells/L | [202] |
Osteomyelitis | 42 | 84 | [203] |