Dual titration of minute ventilation and sweep gas flow to control carbon dioxide variations in patients on venovenous extracorporeal membrane oxygenation

Annals of Intensive Care

Table 1 Clinical characteristics of patients

Variables	All patients (n = 51)	Control group (n = 24)	Protocol group (n = 27)	p
Age	53 [45–58]	56 [50–58]	50 [43–56]	0.03
Male gender (%)	34 (67)	21 (88)	13 (48)	0.003
Body mass index (kg/m²)	31 [27–35]	29 [26–32]	32 [30–39]	0.006
SAPS 2 at ICU admission	35 [29–53]	33 [27–46]	49 [29–57]	0.05
Comorbidities
Diabetes mellitus	14 (27)	8 (33)	6 (22)	0.37
Arterial hypertension	25 (49)	15 (63)	10 (37)	0.07
Ischaemic heart disease	1 (2)	1 (4)	0 (0)	0.47
Chronic renal insufficiency	2 (4)	1 (4)	1 (4)	1
COPD	1 (2)	1 (4)	0 (0)	0.47
Immunodeficiency	3 (6)	2 (8)	1 (4)	0.60
Atrial fibrillation	2 (4)	2 (8)	0 (0)	0.22
Sickle cell disease	1 (2)	1 (4)	0 (0)	0.47
Smoker	8 (16)	6 (25)	2 (16)	0.13

SAPS 2: Simplified Acute Physiology Score 2; ICU intensive care unit; COPD chronic obstructive pulmonary disease