Variables | All patients (n = 51) | Control group (n = 24) | Protocol group (n = 27) | p |
---|---|---|---|---|
VAP | 36 (71) | 15 (63) | 21 (78) | 0.23 |
ICU length of stay (d) | 31 [21–48] | 26 [16–46] | 40 [25–70] | 0.05 |
Duration of mechanical ventilation (d) | 28 [14–49] | 23 [11–41] | 30 [19–56] | 0.16 |
Renal replacement therapy | 24 (47) | 10 (42) | 14 (52) | 0.47 |
ECMO implantation by mobile circulatory assistance unit | 21 (41) | 5 (21) | 16 (59) | 0.01 |
ECMO duration (d) | 16 [9–25] | 13 [6–19] | 21 [12–43] | 0.01 |
Death in hospital | 20 (40) | 11 (46) | 9 (35) | 0.52 |
Cause of death | ||||
Intracranial bleeding | 3 (6) | 3 (13) | 0 (0) | 0.1 |
MOF | 16 (31) | 7 (29) | 9 (33) | 0.74 |
Cardiac arrest | 2 (4) | 1 (4) | 1 (4) | 1 |
Bleeding (ISTH definition) | ||||
Minor bleeding | 4 (8) | 1 (4) | 3 (11) | 0.61 |
Major bleeding | 32 (63) | 16 (67) | 16 (59) | |
Site of bleeding | ||||
Number of performed brain CT | 0 [0–1] | 0 [0–1] | 0 [0–1] | 0.87 |
Number of patients who had at least one brain CT during ECMO run | 18 (35) | 8 (33) | 10 (37) | 0.78 |
Intracranial | 7 (14) | 6 (25) | 1 (4) | 0.04 |
ORL | 21 (41) | 9 (38) | 12 (44) | 0.62 |
Gastro-intestinal | 7 (14) | 3 (13) | 4 (15) | 1 |
Lung | 3 (5) | 1 (4) | 2 (7) | 1 |
Cannula | 20 (39) | 11 (46) | 9 (33) | 0.36 |
Tamponade | 1 (2) | 0 (0) | 1 (4) | 1 |