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Table 4 Haemostatic parameters with ECMO

From: Dual titration of minute ventilation and sweep gas flow to control carbon dioxide variations in patients on venovenous extracorporeal membrane oxygenation

Variables

All patients (n = 51)

Control group (n = 24)

Protocol group (n = 27)

p

ECMO implantationa

 Fibrinogen, g/l

7.3 [5.4–8]

7.6 [5.8–8.6]

6.8 [4.8–7.9]

0.29

 Platelet count, G/l

264 [197–332]

273 [198–350]

261 [196–311]

0.5

During ECMO support

 Lowest fibrinogen, g/L

3.5 [2.6–4.6]

3.8 [3–5.1]

3.1 [2.3–4.4]

0.05

 Lowest platelet count, G/L

111 [63–166]

113 [66–165]

110 [62–171]

0.78

 Median anti-Xa on ECMO, IU/L

0.36 [0.28–0.43]

0.39 [0.31–0.48]

0.32 [0.26–0.38]

0.06

 Number of day with an anti-Xa > 0.7 IU/L

1 [0–1]

0 [0–1]

1 [0–1]

0.4

 Lowest PT, %

57 [47–64]

56 [44–63]

57 [49–70]

0.36

  1. ECMO extracorporeal membrane oxygenation; PT prothrombin time
  2. aWithin the 24 h before or after ECMO implantation; anti-Xa in IU/ml