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  1. The purpose of the present study was to quantify bacterial translocation to mesenteric lymph nodes due to different levels of intra-abdominal hypertension (IAH; 15 vs. 30 mmHg) lasting for 24 h in a porcine mo...

    Authors: Torsten Kaussen, Pramod Kadaba Srinivasan, Mamdouh Afify, Christiane Herweg, René Tolba, Joachim Conze and Alexander Schachtrupp

    Citation: Annals of Intensive Care 2012 2(Suppl 1):S17

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  2. Achievement of a negative fluid balance in patients with capillary leak is associated with improved outcome. We investigated the effects of a multi-modal restrictive fluid strategy aiming for negative fluid ba...

    Authors: Colin Cordemans, Inneke De laet, Niels Van Regenmortel, Karen Schoonheydt, Hilde Dits, Greg Martin, Wolfgang Huber and Manu LNG Malbrain

    Citation: Annals of Intensive Care 2012 2(Suppl 1):S15

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  3. Current assumptions rely on intra-abdominal pressure (IAP) being uniform across the abdominal cavity. The abdominal contents are, however, a heterogeneous mix of solid, liquid and gas, and pressure transmissio...

    Authors: Adrian B Cresswell, Wayel Jassem, Parthi Srinivasan, Andreas A Prachalias, Elizabeth Sizer, William Burnal, Georg Auzinger, Paolo Muiesan, Mohammed Rela, Nigel D Heaton, Matthew J Bowles and Julia A Wendon

    Citation: Annals of Intensive Care 2012 2(Suppl 1):S12

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  4. Several decades ago, the beneficial effects of goal-directed therapy, which include decompressive laparotomy (DL) and open abdomen procedures in cases of intra-abdominal hypertension (IAH) in children, were pr...

    Authors: Torsten Kaussen, Gerd Steinau, Pramod Kadaba Srinivasan, Jens Otto, Michael Sasse, Franz Staudt and Alexander Schachtrupp

    Citation: Annals of Intensive Care 2012 2(Suppl 1):S8

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  5. Abdominal compartment syndrome (ACS) is a life threatening condition that may affect any critically ill patient. Little is known about the recognition and management of ACS in Germany.

    Authors: Torsten Kaussen, Jens Otto, Gerd Steinau, Jörg Höer, Pramod Kadaba Srinivasan and Alexander Schachtrupp

    Citation: Annals of Intensive Care 2012 2(Suppl 1):S7

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  6. The importance of intra-abdominal pressure (IAP) and abdominal perfusion pressure (APP) in cirrhotic patients with septic shock is not well studied. We evaluated the relationship between IAP and APP and outcom...

    Authors: Hasan M Al-Dorzi, Hani M Tamim, Asgar H Rishu, Abdulrahman Aljumah and Yaseen M Arabi

    Citation: Annals of Intensive Care 2012 2(Suppl 1):S4

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  7. The aim of this study was to determine the incidence of intra-abdominal hypertension (IAH) in patients with two or more categorized risk factors (CRF) for IAH, and their morbidity and mortality during their in...

    Authors: Patricia Santa-Teresa, Javier Muñoz, Ignacio Montero, María Zurita, María Tomey, Luis Álvarez-Sala and Pablo García

    Citation: Annals of Intensive Care 2012 2(Suppl 1):S3

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  8. Capillary leak in critically ill patients leads to interstitial edema. Fluid overload is independently associated with poor prognosis. Bedside measurement of intra-abdominal pressure (IAP), extravascular lung ...

    Authors: Colin Cordemans, Inneke De laet, Niels Van Regenmortel, Karen Schoonheydt, Hilde Dits, Wolfgang Huber and Manu LNG Malbrain

    Citation: Annals of Intensive Care 2012 2(Suppl 1):S1

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  9. The purpose of this study was to assess the short- and long-term outcomes of HIV-infected patients admitted to intensive care units (ICU) according to immunovirological status at admission and highly active an...

    Authors: David Morquin, Vincent Le Moing, Thibaut Mura, Alain Makinson, Kada Klouche, Olivier Jonquet, Jacques Reynes and Philippe Corne

    Citation: Annals of Intensive Care 2012 2:25

    Content type: Research

    Published on:

  10. Because of its still rising incidence and high mortality rate in intensive care unit (ICU) patients, early recognition of acute kidney injury (AKI) remains a critical issue. Surprisingly, effective biomarkers ...

    Authors: Patrick M Honore, Rita Jacobs, Olivier Joannes-Boyau, Lies Verfaillie, Jouke De Regt, Viola Van Gorp, Elisabeth De Waele, Willem Boer, Vincent Collin and Herbert D Spapen

    Citation: Annals of Intensive Care 2012 2:24

    Content type: Review

    Published on:

  11. French law allows organ donation after death due to cardiocirculatory arrest. In the Maastricht classification, type III non-heart-beating donors are those who experience cardiocirculatory arrest after the wit...

    Authors: Jean-Pierre Graftieaux, Pierre-Edouard Bollaert, Lise Haddad, Nancy Kentish-Barnes, Gérard Nitenberg, René Robert, Daniel Villers and Didier Dreyfuss

    Citation: Annals of Intensive Care 2012 2:23

    Content type: Review

    Published on:

  12. The alarming global rise of antimicrobial resistance combined with the lack of new antimicrobial agents has led to a renewed interest in optimization of our current antibiotics. Continuous infusion (CI) of tim...

    Authors: Bruno Van Herendael, Axel Jeurissen, Paul M Tulkens, Erika Vlieghe, Walter Verbrugghe, Philippe G Jorens and Margareta Ieven

    Citation: Annals of Intensive Care 2012 2:22

    Content type: Review

    Published on:

  13. Previous studies have shown a good agreement between central venous pressure (CVP) measurements from catheters placed in superior vena cava and catheters placed in the abdominal cava/common iliac vein. However...

    Authors: Hafid Ait-Oufella, Pierre-Yves Boelle, Arnaud Galbois, Jean-luc Baudel, Dimitri Margetis, Mikael Alves, Georges Offenstadt, Eric Maury and Bertrand Guidet

    Citation: Annals of Intensive Care 2012 2:21

    Content type: Research

    Published on:

  14. Rapid response systems (RRSs) are considered an important tool for improving patient safety. We studied the effect of an RRS on the incidence of cardiac arrests and unexpected deaths.

    Authors: Friede M Simmes, Lisette Schoonhoven, Joke Mintjes, Bernard G Fikkers and Johannes G van der Hoeven

    Citation: Annals of Intensive Care 2012 2:20

    Content type: Research

    Published on:

  15. The use or misuse of statins in critically ill patients recently attracted the attention of intensive care clinicians. Indeed, statins are probably the most common chronic treatment before critical illness and...

    Authors: Isabelle De Loecker and Jean-Charles Preiser

    Citation: Annals of Intensive Care 2012 2:19

    Content type: Review

    Published on:

  16. Critical care delivery is a complex, expensive, error prone, medical specialty and remains the focal point of major improvement efforts in healthcare delivery. Various modeling and simulation techniques offer ...

    Authors: Yue Dong, Nicolas W Chbat, Ashish Gupta, Mirsad Hadzikadic and Ognjen Gajic

    Citation: Annals of Intensive Care 2012 2:18

    Content type: Review

    Published on:

  17. Effective tight glycemic control (TGC) can improve outcomes in critical care patients, but it is difficult to achieve consistently. Insulin sensitivity defines the metabolic balance between insulin concentrati...

    Authors: Christopher G Pretty, Aaron J Le Compte, J Geoffrey Chase, Geoffrey M Shaw, Jean-Charles Preiser, Sophie Penning and Thomas Desaive

    Citation: Annals of Intensive Care 2012 2:17

    Content type: Research

    Published on:

  18. We assessed the potential impact of infusion tubing on blood glucose imbalance in ICU patients given intensive insulin therapy (IIT). We compared the incidence of blood glucose imbalance in patients equipped, ...

    Authors: Eric Maury, Paola Vitry, Arnauld Galbois, Hafid Ait-Oufella, Jean-Luc Baudel, Bertrand Guidet and Georges Offenstadt

    Citation: Annals of Intensive Care 2012 2:16

    Content type: Research

    Published on:

  19. A genomic biomarker identifying patients likely to benefit from drotrecogin alfa (activated) (DAA) may be clinically useful as a companion diagnostic. This trial was designed to validate biomarkers (improved r...

    Authors: Djillali Annane, Jean Paul Mira, Lorraine B Ware, Anthony C Gordon, Jonathan Sevransky, Frank Stüber, Patrick J Heagerty, Hugh F Wellman, Mauricio Neira, Alexandra DJ Mancini and James A Russell

    Citation: Annals of Intensive Care 2012 2:15

    Content type: Research

    Published on:

  20. Cancer is a leading cause of death in children. In the past decades, there has been a marked increase in overall survival of children with cancer. However, children whose treatment includes hematopoietic stem ...

    Authors: Pierre Demaret, Geraldine Pettersen, Philippe Hubert, Pierre Teira and Guillaume Emeriaud

    Citation: Annals of Intensive Care 2012 2:14

    Content type: Review

    Published on:

  21. Hyponatremia occurring as a result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or cerebral salt wasting syndrome is a common complication in patients with subarachnoid hemorrhage (S...

    Authors: Charalampos Pierrakos, Fabio Silvio Taccone, Guy Decaux, Jean-Louis Vincent and Serge Brimioulle

    Citation: Annals of Intensive Care 2012 2:13

    Content type: Research

    Published on:

  22. Central nervous system infection is a daily concern in neurointensive care; however, diagnosis remains difficult because classical criteria based on cerebrospinal fluid (CSF) analysis are difficult to interpre...

    Authors: Anne-Claire Lukaszewicz, Géraldine Gontier, Valérie Faivre, Ingrid Ouanounou and Didier Payen

    Citation: Annals of Intensive Care 2012 2:10

    Content type: Research

    Published on:

  23. The passive leg-raising (PLR) maneuver provides a dynamic assessment of fluid responsiveness inducing a reversible increase in cardiac preload. Since its effects are sudden and transitory, a continuous cardiac...

    Authors: Manuel Ignacio Monge García, Anselmo Gil Cano, Manuel Gracia Romero, Rocío Monterroso Pintado, Virginia Pérez Madueño and Juan Carlos Díaz Monrové

    Citation: Annals of Intensive Care 2012 2:9

    Content type: Research

    Published on:

  24. Cardiac biomarkers (CB) were first developed for assisting the diagnosis of cardiac events, especially acute myocardial infarction. The discoveries of other CB, the better understanding of cardiac disease proc...

    Authors: Anthony S McLean and Stephen J Huang

    Citation: Annals of Intensive Care 2012 2:8

    Content type: Review

    Published on:

  25. Numerous cases of swine-origin 2009 H1N1 influenza A virus (H1N1)-associated acute respiratory distress syndrome (ARDS) bridged by extracorporeal membrane oxygenation (ECMO) therapy have been reported; however...

    Authors: Tobias M Bingold, Bertram Scheller, Timo Wolf, Jens Meier, Alexander Koch, Kai Zacharowski, Peter Rosenberger and Thomas Iber

    Citation: Annals of Intensive Care 2012 2:7

    Content type: Research

    Published on:

  26. Candida and Aspergillus spp. are the most common agents responsible for invasive fungal infections in children. They are associated with a high mortality and morbidity rate as well as high health care costs. An ...

    Authors: Olivier Brissaud, Julie Guichoux, Jerome Harambat, Olivier Tandonnet and Theoklis Zaoutis

    Citation: Annals of Intensive Care 2012 2:6

    Content type: Review

    Published on:

  27. Noninvasive ventilation (NIV) is frequently used for the management of acute respiratory failure (ARF) in very old patients (≥ 80 years), often in the context of a do-not-intubate order (DNI). We aimed to dete...

    Authors: Frederique Schortgen, Arnaud Follin, Lucilla Piccari, Ferran Roche-Campo, Guillaume Carteaux, Elodie Taillandier-Heriche, Sebastien Krypciak, Arnaud W Thille, Elena Paillaud and Laurent Brochard

    Citation: Annals of Intensive Care 2012 2:5

    Content type: Research

    Published on:

  28. Neurologists often diagnose brain death (BD) and explain BD to families in the intensive care unit. This study was designed to determine whether neurologists agree with the standard concept of death (irreversi...

    Authors: Ari R Joffe, Natalie R Anton, Jonathan P Duff and Allan deCaen

    Citation: Annals of Intensive Care 2012 2:4

    Content type: Research

    Published on:

  29. Safety is a global concept that encompasses efficiency, security of care, reactivity of caregivers, and satisfaction of patients and relatives. Patient safety has emerged as a major target for healthcare impro...

    Authors: Maité Garrouste-Orgeas, François Philippart, Cédric Bruel, Adeline Max, Nicolas Lau and B Misset

    Citation: Annals of Intensive Care 2012 2:2

    Content type: Review

    Published on:

  30. Critically ill adult patients often require multiple examinations in the hospital and need transport from one department to another, or even between hospitals. However, to date, no guidelines exist regarding o...

    Authors: Jean-Pierre Quenot, Christophe Milési, Aurély Cravoisy, Gilles Capellier, Olivier Mimoz, Olivier Fourcade and Pierre-Yves Gueugniaud

    Citation: Annals of Intensive Care 2012 2:1

    Content type: Review

    Published on:

  31. Sepsis continues to be a poorly understood syndrome with a high mortality rate. While we are beginning to decipher the intricate interplay of the inflammatory response during sepsis, the precise regulation of ...

    Authors: Michael A Flierl, Daniel Rittirsch, Sebastian Weckbach, Markus Huber-Lang, Kyros Ipaktchi, Peter A Ward and Philip F Stahel

    Citation: Annals of Intensive Care 2011 1:53

    Content type: Research

    Published on:

  32. Community-acquired necrotizing pneumonia caused by Panton-Valentine leukocidin (PVL)-secreting Staphylococcus aureus is a highly lethal infection that mainly affects healthy children and young adults. Both methic...

    Authors: Lukas Kreienbuehl, Emmanuel Charbonney and Philippe Eggimann

    Citation: Annals of Intensive Care 2011 1:52

    Content type: Research

    Published on:

  33. Although prompt initiation of appropriate antifungal therapy is essential for the control of invasive Candida infections and an improvement of prognosis, early diagnosis of invasive candidiasis remains a challeng...

    Authors: Guillaume Leroy, Fabien Lambiotte, Didier Thévenin, Christian Lemaire, Erika Parmentier, Patrick Devos and Olivier Leroy

    Citation: Annals of Intensive Care 2011 1:50

    Content type: Research

    Published on:

  34. Hypoglycemia is associated with increased mortality in critically ill patients. The impact of hypoglycemia on resource utilization has not been investigated. The objective of this investigation was to evaluate...

    Authors: James Krinsley, Marcus J Schultz, Peter E Spronk, Floris van Braam Houckgeest, Johannes P van der Sluijs, Christian Mélot and Jean-Charles Preiser

    Citation: Annals of Intensive Care 2011 1:49

    Content type: Research

    Published on:

  35. Microcirculation plays a vital role in the development of multiple organ failure in severe sepsis. The effects of red blood cell (RBC) transfusions on these tissue oxygenation and microcirculation variables in...

    Authors: Farid Sadaka, Ravi Aggu-Sher, Katie Krause, Jacklyn O'Brien, Eric S Armbrecht and Robert W Taylor

    Citation: Annals of Intensive Care 2011 1:46

    Content type: Research

    Published on:

  36. The prognosis for postcardiac arrest patients remains very bleak, not only because of anoxic-ischemic neurological damage, but also because of the "postcardiac arrest syndrome," a phenomenon often severe enoug...

    Authors: Nicolas Mongardon, Florence Dumas, Sylvie Ricome, David Grimaldi, Tarik Hissem, Frédéric Pène and Alain Cariou

    Citation: Annals of Intensive Care 2011 1:45

    Content type: Review

    Published on:

  37. This study was designed to investigate the effect of hypertonic fluid administration on inflammatory mediator gene expression in patients with septic shock.

    Authors: Frank MP van Haren, James Sleigh, Ray Cursons, Mary La Pine, Peter Pickkers and Johannes G van der Hoeven

    Citation: Annals of Intensive Care 2011 1:44

    Content type: Research

    Published on:

  38. Red blood cell (RBC) transfusion is a common intervention in intensive care unit (ICU) patients. Anemia is frequent in this population and is associated with poor outcomes, especially in patients with ischemic...

    Authors: Christophe Lelubre and Jean-Louis Vincent

    Citation: Annals of Intensive Care 2011 1:43

    Content type: Review

    Published on:

  39. Mechanical ventilation seems to occupy a major source in alteration in the quality and quantity of sleep among patients in intensive care. Quality of sleep is negatively affected with frequent patient-ventilat...

    Authors: Stéphane Delisle, Paul Ouellet, Patrick Bellemare, Jean-Pierre Tétrault and Pierre Arsenault

    Citation: Annals of Intensive Care 2011 1:42

    Content type: Research

    Published on:

  40. Mitochondrial functions include production of energy, activation of programmed cell death, and a number of cell specific tasks, e.g., cell signaling, control of Ca2+ metabolism, and synthesis of a number of impor...

    Authors: Andrey V Kozlov, Soheyl Bahrami, Enrico Calzia, Peter Dungel, Lars Gille, Andrey V Kuznetsov and Jakob Troppmair

    Citation: Annals of Intensive Care 2011 1:41

    Content type: Review

    Published on:

  41. Erythropoietin (EPO) is the major hormone stimulating the production and differentiation of red blood cells. EPO is used widely for treating anemia of critical illness or anemia induced by chemotherapy. EPO at...

    Authors: Nimesh SA Patel, Massimo Collino, Muhammad M Yaqoob and Christoph Thiemermann

    Citation: Annals of Intensive Care 2011 1:40

    Content type: Review

    Published on:

  42. Stress-related cardiomyopathies can be observed in the four following situations: Takotsubo cardiomyopathy or apical ballooning syndrome; acute left ventricular dysfunction associated with subarachnoid hemorrh...

    Authors: Christian Richard

    Citation: Annals of Intensive Care 2011 1:39

    Content type: Review

    Published on:

  43. Tight glycemic control (TGC) has shown benefits but has been difficult to achieve consistently. STAR (Stochastic TARgeted) is a flexible, model-based TGC approach directly accounting for intra- and inter- pati...

    Authors: Alicia Evans, Geoffrey M Shaw, Aaron Le Compte, Chia-Siong Tan, Logan Ward, James Steel, Christopher G Pretty, Leesa Pfeifer, Sophie Penning, Fatanah Suhaimi, Matthew Signal, Thomas Desaive and J Geoffrey Chase

    Citation: Annals of Intensive Care 2011 1:38

    Content type: Research

    Published on:

  44. Invasive candidiasis ranges from 5 to 10 cases per 1,000 ICU admissions and represents 5% to 10% of all ICU-acquired infections, with an overall mortality comparable to that of severe sepsis/septic shock. A la...

    Authors: Philippe Eggimann, Jacques Bille and Oscar Marchetti

    Citation: Annals of Intensive Care 2011 1:37

    Content type: Review

    Published on:

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