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  1. Norepinephrine is a key drug for treating shock but has a short half-life that requires continuous intravenous administration to maintain the constant plasma concentration needed to obtain a stable blood press...

    Authors: Emilie Greau, Jean-Baptiste Lascarrou, Aurélie Le Thuaut, Nathalie Maquigneau, Yolaine Alcourt, Anne Coutolleau, Cécile Rousseau, Vanessa Erragne and Jean Reignier
    Citation: Annals of Intensive Care 2015 5:40
  2. Hyponatremia is a common electrolyte derangement in the setting of the intensive care unit. Life-threatening neurological complications may arise not only in case of a severe (<120 mmol/L) and acute fall of p...

    Authors: Cédric Rafat, Martin Flamant, Stéphane Gaudry, Emmanuelle Vidal-Petiot, Jean-Damien Ricard and Didier Dreyfuss
    Citation: Annals of Intensive Care 2015 5:39
  3. There is much controversy around the optimal caloric intake in intensive care unit (ICU) patients, based on the diverging results of prospective studies. Therefore, we assessed the presence of an association b...

    Authors: Isabel Carolina Reis Crosara, Christian Mélot and Jean-Charles Preiser
    Citation: Annals of Intensive Care 2015 5:37
  4. In critically ill children, in-line microfilters may reduce the incidence of the systemic inflammatory response syndrome (SIRS), the overall complication and organ dysfunction rate. No data on the use of in-li...

    Authors: Ilse Gradwohl-Matis, Andreas Brunauer, Daniel Dankl, Elisabeth Wirthel, Ingeborg Meburger, Angela Bayer, Michaela Mandl, Martin W. Dünser and Wilhelm Grander
    Citation: Annals of Intensive Care 2015 5:36
  5. Data are sparse regarding the effects of prolonged prone positioning (PP) during VV-ECMO. Previous studies, using short sessions (<12 h), failed to find any effects on respiratory system compliance. In the pre...

    Authors: Antoine Kimmoun, Sylvain Roche, Céline Bridey, Fabrice Vanhuyse, Renaud Fay, Nicolas Girerd, Damien Mandry and Bruno Levy
    Citation: Annals of Intensive Care 2015 5:35
  6. We retrospectively studied associations between bolus infusion of hydrocortisone and variability of the blood glucose level and changes in insulin rates in intensive care unit (ICU) patients.

    Authors: Roosmarijn T. M. van Hooijdonk, Jan M. Binnekade, Lieuwe D. J. Bos, Janneke Horn, Nicole P. Juffermans, Ameen Abu-Hanna and Marcus J. Schultz
    Citation: Annals of Intensive Care 2015 5:34
  7. Dexmedetomidine (DEX) is a centrally acting alpha-2-adrenoceptor agonist that has potential in the management of alcohol withdrawal syndrome (AWS) owing to its ability to produce arousable sedation and to inhi...

    Authors: Kateryna Bielka, Iurii Kuchyn and Felix Glumcher
    Citation: Annals of Intensive Care 2015 5:33
  8. Empiric antibiotic therapy is routinely prescribed in patients with acute COPD exacerbations (AECOPD) requiring ventilatory support on the basis of studies including patients conventionally ventilated. Whether...

    Authors: Islem Ouanes, Lamia Ouanes-Besbes, Saoussen Ben Abdallah, Fahmi Dachraoui and Fekri Abroug
    Citation: Annals of Intensive Care 2015 5:30
  9. Sepsis and septic shock is characterized by oxidative stress that mainly promotes systemic inflammation and organ failure due to excessive free radical production and depletion of antioxidant defenses. Theref...

    Authors: Legese Chelkeba, Arezoo Ahmadi, Mohammad Abdollahi, Atabak Najafi, Mohammad Hosein Ghadimi, Reza Mosaed and Mojtaba Mojtahedzadeh
    Citation: Annals of Intensive Care 2015 5:29
  10. In patients with hematological malignancies and acute respiratory failure (ARF), noninvasive ventilation was associated with a decreased mortality in older studies. However, mortality of intubated patients dec...

    Authors: Virginie Lemiale, Matthieu Resche-Rigon, Djamel Mokart, Frederic Pène, Antoine Rabbat, Achille Kouatchet, François Vincent, Fabrice Bruneel, Martine Nyunga, Christine Lebert, Pierre Perez, Anne-Pascale Meert, Dominique Benoit, Sylvie Chevret and Elie Azoulay
    Citation: Annals of Intensive Care 2015 5:28
  11. The aims of this study were to prospectively assess the prevalence of sustained (lasting more than 30 s) new-onset supraventricular arrhythmia (NOSVA) during septic shock, identify the associated factors (incl...

    Authors: Aurélien Seemann, Florence Boissier, Keyvan Razazi, Guillaume Carteaux, Nicolas de Prost, Christian Brun-Buisson and Armand Mekontso Dessap
    Citation: Annals of Intensive Care 2015 5:27
  12. Authors: Bruno Levy, Olivier Bastien, Karim Bendjelid, Alain Cariou, Tahar Chouihed, Alain Combes, Alexandre Mebazaa, Bruno Megarbane, Patrick Plaisance, Alexandre Ouattara, Christian Spaulding, Jean-Louis Teboul, Fabrice Vanhuyse, Thierry Boulain and Kaldoun Kuteifan
    Citation: Annals of Intensive Care 2015 5:26

    The original article was published in Annals of Intensive Care 2015 5:17

  13. High-frequency oscillatory ventilation (HFOV) does not improve the prognosis of ARDS patients despite an improvement in oxygenation. This paradox may partly be explained by HFOV hemodynamic side-effects on rig...

    Authors: Lionel Ursulet, Arnaud Roussiaux, Dominique Belcour, Cyril Ferdynus, Bernard-Alex Gauzere, David Vandroux and Julien Jabot
    Citation: Annals of Intensive Care 2015 5:25
  14. Discharge destination after critical illness is increasingly recognized as a valuable patient-centered outcome. Recently, vitamin D status has been shown to be associated with important outcomes such as length...

    Authors: Karolina Brook, Carlos A. Camargo, Kenneth B. Christopher and Sadeq A. Quraishi
    Citation: Annals of Intensive Care 2015 5:23
  15. Jean-Luc Diehl The French Intensive Care Society organized on 5th and 6th June 2014 its 4th “Paris International Conference in Intensive Care”, whose principle is to bring together the be...

    Authors: Peter J. Kudenchuk, Claudio Sandroni, Hendrik R. Drinhaus, Bernd W. Böttiger, Alain Cariou, Kjetil Sunde, Martin Dworschak, Fabio Silvio Taccone, Nicolas Deye, Hans Friberg, Steven Laureys, Didier Ledoux, Mauro Oddo, Stéphane Legriel, Philippe Hantson, Jean-Luc Diehl…
    Citation: Annals of Intensive Care 2015 5:22
  16. The burden of multidrug resistance in Gram-negative bacilli (GNB) now represents a daily issue for the management of antimicrobial therapy in intensive care unit (ICU) patients. In Enterobacteriaceae, the dramati...

    Authors: Étienne Ruppé, Paul-Louis Woerther and François Barbier
    Citation: Annals of Intensive Care 2015 5:21
  17. To improve the delivery of important care processes in the ICU, morning ward round checklists have been implemented in a number of intensive care units (ICUs) internationally. Good quality evidence supporting ...

    Authors: Karena M Conroy, Doug Elliott and Anthony R Burrell
    Citation: Annals of Intensive Care 2015 5:20
  18. We aim to demonstrate behavioral alterations in a sepsis model using intravenous (IV) immunoglobulin G (IgG) and immunoglobulins enriched with IgA and IgM (IgGAM).

    Authors: Perihan Ergin Ozcan, Evren Senturk, Gunseli Orhun, Salih Gumru, Nadir Arican, Nurcan Orhan, Canan Ugur Yılmaz, Mehmet Kaya, Feyza Aricioglu and Figen Esen
    Citation: Annals of Intensive Care 2015 5:19
  19. There have been few studies that have evaluated the quality of end-of-life care (EOLC) for cancer patients in the ICU. The aim of this study was to explore the quality of transition to EOLC for cancer patient...

    Authors: Sophie J Miller, Nishita Desai, Natalie Pattison, Joanne M Droney, Angela King, Paul Farquhar-Smith and Pascale C Gruber
    Citation: Annals of Intensive Care 2015 5:18
  20. Unlike for septic shock, there are no specific international recommendations regarding the management of cardiogenic shock (CS) in critically ill patients. We present herein recommendations for the management ...

    Authors: Bruno Levy, Olivier Bastien, Karim Bendjelid, Alain Cariou, Tahar Chouihed, Alain Combes, Alexandre Mebazaa, Bruno Megarbane, Patrick Plaisance, Alexandre Ouattara, Christian Spaulding, Jean-Louis Teboul, Fabrice Vanhuyse, Thierry Boulain and Kaldoun Kuteifan
    Citation: Annals of Intensive Care 2015 5:17

    The Erratum to this article has been published in Annals of Intensive Care 2015 5:26

  21. Most studies about septic shock report a crude mortality rate that neither distinguishes between early and late deaths nor addresses the direct causes of death. We herein aimed to determine the modalities of d...

    Authors: Fabrice Daviaud, David Grimaldi, Agnès Dechartres, Julien Charpentier, Guillaume Geri, Nathalie Marin, Jean-Daniel Chiche, Alain Cariou, Jean-Paul Mira and Frédéric Pène
    Citation: Annals of Intensive Care 2015 5:16
  22. In France, decisions to limit treatment fall under the Leonetti law adopted in 2005. Leading figures from the French world of politics, science, and justice recently claimed for amendments to the law, consider...

    Authors: Olivier Lesieur, Maxime Leloup, Frédéric Gonzalez and Marie-France Mamzer
    Citation: Annals of Intensive Care 2015 5:15
  23. Patients with severe cardiogenic pulmonary edema (CPE) are frequently hypercapnic, possibly because of associated underlying chronic lung disease (CLD). Since hypercapnia has been associated with outcome, we a...

    Authors: Damien Contou, Chiara Fragnoli, Ana Córdoba-Izquierdo, Florence Boissier, Christian Brun-Buisson and Arnaud W Thille
    Citation: Annals of Intensive Care 2015 5:14
  24. Cuff pressure (P cuff) control is mandatory to avoid leakage of oral secretions passing the tracheal tube and tracheal ischemia. The aim of the present trial was to determine the efficacy of a m...

    Authors: Saad Nseir, Andrey Rodriguez, Paula Saludes, Julien De Jonckheere, Jordi Valles, Antonio Artigas and Ignacio Martin-Loeches
    Citation: Annals of Intensive Care 2015 5:12
  25. Vancomycin during continuous venovenous hemofiltration (CVVH) is either administered by intermittent infusion (II) or continuous infusion (CI). In this patient population, the best method to rapidly achieve ta...

    Authors: Hsin Lin, Yana Bukovskaya, Marc De Moya, Jarone Lee and Ulrich Schmidt
    Citation: Annals of Intensive Care 2015 5:10
  26. The purpose of this study is to compare the in-hospital mortality rates between septic patients receiving statins and those that did not prior to developing sepsis. We compared subgroups receiving atorvastatin...

    Authors: Daniel R Ouellette, Erics Espinoza Moscoso, Julio Pinto Corrales and Michael Peters
    Citation: Annals of Intensive Care 2015 5:9
  27. Experimental research has always been the cornerstone of pathophysiological and therapeutic advances in critical care medicine, where clinical observations and basic research mutually fed each other in a so-ca...

    Authors: Frédéric Pène, Hafid Ait-Oufella, Fabio Silvio Taccone, Guillaume Monneret, Tarek Sharshar, Fabienne Tamion and Jean-Paul Mira
    Citation: Annals of Intensive Care 2015 5:8
  28. The triage nurse is involved in the early identification of the most severe patients at emergency department (ED) presentation. However, clinical criteria alone may be insufficient to identify them correctly. ...

    Authors: Cyril Manzon, Loïc Barrot, Guillaume Besch, Olivier Barbot, Thibaut Desmettre, Gilles Capellier and Gaël Piton
    Citation: Annals of Intensive Care 2015 5:7
  29. Web-based decision aids are increasingly important in medical research and clinical care. However, few have been studied in an intensive care unit setting. The objectives of this study were to develop a Web-ba...

    Authors: Christopher E Cox, Nicholas G Wysham, Brenda Walton, Derek Jones, Brian Cass, Maria Tobin, Mattias Jonsson, Jeremy M Kahn, Douglas B White, Catherine L Hough, Carmen L Lewis and Shannon S Carson
    Citation: Annals of Intensive Care 2015 5:6
  30. Transpulmonary bubble transit (TPBT) detected with contrast echocardiography is reported as a sign of intrapulmonary shunt during cirrhosis or exercise in healthy humans. However, its physiological meaning is ...

    Authors: Florence Boissier, Keyvan Razazi, Arnaud W Thille, Ferran Roche-Campo, Rusel Leon, Emmanuel Vivier, Laurent Brochard, Christian Brun-Buisson and Armand Mekontso Dessap
    Citation: Annals of Intensive Care 2015 5:5
  31. Noninvasive positive-pressure ventilation (NIPPV) use has increased in the treatment of patients with respiratory failure. However, despite decreasing the need for intubation in some patients, there are no dat...

    Authors: Jarrod M Mosier, John C Sakles, Sage P Whitmore, Cameron D Hypes, Danielle K Hallett, Katharine E Hawbaker, Linda S Snyder and John W Bloom
    Citation: Annals of Intensive Care 2015 5:4
  32. In acute respiratory failure, arterial blood gas analysis (ABG) is used to diagnose hypercapnia. Once non-invasive ventilation (NIV) is initiated, ABG should at least be repeated within 1 h to assess PaCO2 respon...

    Authors: Lise Piquilloud, David Thevoz, Philippe Jolliet and Jean-Pierre Revelly
    Citation: Annals of Intensive Care 2015 5:2
  33. The purpose of the study was to assess blood flow in the upper limb arteries after prolonged catheterization with long radial artery catheters (LRC) which reach the subclavian artery compared to catheterizatio...

    Authors: Lucas Rovira, Gerardo Aguilar, Alberto Cuñat and Francisco J Belda
    Citation: Annals of Intensive Care 2015 5:1
  34. Availability of a patient data management system (PDMS) has created the opportunity to develop trigger-based electronic surveillance systems (ESSs). The aim was to evaluate a semi-automated trigger-based ESS f...

    Authors: Anna Maria Kaiser, Evelien de Jong, Sabine FM Evelein-Brugman, Jan M Peppink, Christina MJE Vandenbroucke-Grauls and Armand RJ Girbes
    Citation: Annals of Intensive Care 2014 4:40
  35. This study was performed to compare intestinal and sublingual microcirculation and their response to a fluid challenge.

    Authors: Vanina Siham Kanoore Edul, Can Ince, Noelia Navarro, Luciana Previgliano, Alejandro Risso-Vazquez, Paolo Nahuel Rubatto and Arnaldo Dubin
    Citation: Annals of Intensive Care 2014 4:39
  36. Even in developed countries, severe specific pregnancy complications may occur in the immediate postpartum period and require admission to the ICU. The characteristics and risk factors of acute renal failure (ARF...

    Authors: Marie Jonard, Anne-Sophie Ducloy-Bouthors, Eileen Boyle, Maryse Aucourt, Gaelle Gasan, Merce Jourdain, Virginie Mignaux, Nadia Tillouche and François Fourrier
    Citation: Annals of Intensive Care 2014 4:36
  37. In critically ill patients with pneumonia, accurate microorganism identification allows appropriate antibiotic treatment. In patients undergoing bronchoalveolar lavage (BAL), direct examination of the fluid us...

    Authors: Jean-Luc Baudel, Jacques Tankovic, Redouane Dahoumane, Fabrice Carrat, Arnaud Galbois, Hafid Ait-Oufella, Georges Offenstadt, Bertrand Guidet and Eric Maury
    Citation: Annals of Intensive Care 2014 4:35
  38. Healthcare-associated bloodstream infections are related to both increased antibiotic use and risk of adverse outcomes. An in-depth understanding of their epidemiology is essential to reduce occurrence and to ...

    Authors: Nick Culshaw, Guy Glover, Craig Whiteley, Katie Rowland, Duncan Wyncoll, Andrew Jones and Manu Shankar-Hari
    Citation: Annals of Intensive Care 2014 4:34
  39. The Lung Open Ventilation Study (LOV Study) compared a low tidal volume strategy with an experimental strategy combining low tidal volume, lung recruitment maneuvers, and higher plateau and positive end-expira...

    Authors: Sangeeta Mehta, Deborah J Cook, Yoanna Skrobik, John Muscedere, Claudio M Martin, Thomas E Stewart, Lisa D Burry, Qi Zhou and Maureen Meade
    Citation: Annals of Intensive Care 2014 4:33
  40. Guidelines on systemic corticosteroids in chronic obstructive pulmonary disease (COPD) exacerbation rely on studies that excluded patients requiring ventilatory support. Recent publication of studies including...

    Authors: Fekri Abroug, Islem Ouanes, Sarra Abroug, Fahmi Dachraoui, Saoussen Ben Abdallah, Zeineb Hammouda and Lamia Ouanes-Besbes
    Citation: Annals of Intensive Care 2014 4:32
  41. The decision of when to stop septic shock resuscitation is a critical but yet a relatively unexplored aspect of care. This is especially relevant since the risks of over-resuscitation with fluid overload or in...

    Authors: Glenn Hernandez, Cecilia Luengo, Alejandro Bruhn, Eduardo Kattan, Gilberto Friedman, Gustavo A Ospina-Tascon, Andrea Fuentealba, Ricardo Castro, Tomas Regueira, Carlos Romero, Can Ince and Jan Bakker
    Citation: Annals of Intensive Care 2014 4:30

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